Diamond DEAE Mustang ion exchange resins

Ion exchange chromatography(IEC)is a very effective method for the separation and purification of biomolecule. The method mainly relies on the interaction between positive and negative charges, and uses the charge properties and differences of different biological molecules under specific conditions to separate them. It has the characteristics of high load, good resolution, controllable condition and easy scale-up. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

IEC resin is composed of three parts: (1)Cross-linked agarose matrix, that has the characteristics of porous, hydrophilic and good chemical stability; Traditional agarose molecules are modified to have better mechanical properties, which is called high rigid agarose, or Diamond base matrix. (2)Functional groups fixed to the matrix, which are electrically charged groups, determining the properties of the IEC resin; (3)An ion (called an equilibrium ion) that has an opposite charge to the functional group and can be reversibly bound to the functional group.

Diamond DEAE Mustang is a weak anion exchange resin formed by coupling diethylaminoethyl on small and highly rigid agarose microspheres. Diamond DEAE has a higher resolution than Diamond DEAE and is suitable for fine or resin purification stages in the chromatography step.