Di-tert-butyl dicarbonate

Category:Excipients > Correctives
Product Name:Di-tert-butyl dicarbonate
CAS No.:7365-44-8
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):US$39~US$67/Kg
Company:Jiangsu Magic Biotechnology Co., Ltd

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: No.016, Fengwang Road, Wanggou Town, Feng County, Xuzhou City, Jiangsu Province

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 500MT

    Contract Manufacturing: CRO,CMO

  • Delivery Lead Time: 1

    Sample Provided: yes

    Payment Terms: L/C

    The compound, with the molecular formula C10H18O5, is used in organic synthesis to introduce tert butoxycarbonyl protecting groups, especially for the protection of amino acids such as amino acids. The application of di tert butyl dicarbonate as a carboxylic acid ester derivative can be widely used in the synthesis of various products such as medicine, protein and peptide synthesis, biochemical food, cosmetics, etc. Boc anhydride is a flammable liquid with chemical properties. Melting point 23 ℃, boiling point 56-57 ℃ (6.55E-2kPa). Reference quality standard Appearance: Low melting point crystal solid purity (HPLC) ≥ 99.0% Melting point: 23 ° C (lit.) Boiling point: 65-67 ° C Refractive index: n20/D1.409 (lit.) Drying loss:? ≤ 0.5% is used as an intermediate in pharmaceutical and organic synthesis, and is an important amino protectant used in the synthesis of pharmaceutical and agricultural products. It is used in organic synthesis to introduce tert butoxycarbonyl protecting groups. Application: Di tert butyl dicarbonate (Boc anhydride) is used in organic synthesis to introduce tert butoxycarbonyl protection genes, especially for amino acid protection. Widely used in the synthesis of various products such as pharmaceuticals, Chemicalbook protein and peptide synthesis, biochemical food, cosmetics, etc. Application: Amino acid BOC reagent. Used in organic synthesis to introduce tert butoxycarbonyl (BOC) protecting groups, particularly suitable for amino protection of amino acids. Can hydrazine protected by tert butoxycarbonyl be used to prepare fluorenylmethoxycarbonyl in chromogenic reagents? Esters are used to monitor solid-phase aldehydes. Reagent for preparing amine protected by tert butoxycarbonyl group. Reagent used to introduce tert butoxycarbonyl protecting groups. Lewis acid catalysis can protect alcohols such as tert butoxycarbonyl derivatives. Through the reaction of tert butoxycarbonylaminopropyne with formaldehyde, diisopropylamine, and copper bromide? Reaction is used to prepare aminomethylpropane, which is an inactivating agent for many bovine plasma amine oxidase enzymes? The components. Production method: Potassium tert butoxide is dissolved in anhydrous tetrahydrofuran, and dry carbon dioxide is introduced at -5~-20 ℃ to produce a slurry. The low temperature is continued, and phosgene benzene solution is added dropwise to obtain di tert butyl tricarbonate. Dissolve it in carbon tetrachloride, add an appropriate amount of 1,4-diazabicyclo [2,2] octane, stir at 25 ℃ to completely release carbon dioxide, and convert it to di tert butyl dicarbonate.

     

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