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Category:Excipients > Disintegrants > Tablet Disintegrants
Product Name:Crospovidone XL\XL10\SF, PVPP Type A/B
CAS No.:25249-54-1/9003-39-8
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):Negotiable
Company:Shanghai Yuking New Material Technology Co., Ltd..
Grade: Pharmaceutical Grade
Factory Location: No.101,Guanyu Road,Hi-Tech District,Xiangyang,Hubei(factory)
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 5000kg
Packaging Information: 20kg/drum
Delivery Lead Time: Negotiable
Sample Provided: yes
Payment Terms: T/T
Product description:
Crospovidone is a white or nearly white, hygroscopic and easy-flowing powder, odorless or slightly odorous, insoluble in water, alkali, acid and common organic solvents, with strong swelling properties and complexing ability with many types of substances.
Pharmacopoeia name: Crospovidone, Crospovidonum (USP), Crospovidone (EP)
Chemical name: Cross-linked polyvinyl pyrrolidone
INCI/CTFA:Insoluble PVP
CAS number:9003-39-8、25249-54-1
Main properties: This product has a high capillary/water content, large specific surface area, extremely strong hydration ability, high and rapid water absorption, strong water absorption and swelling ability, and has the same complexing ability as polyvinyl pyrrolidone, and can complex with a variety of substances, such as phenols, iodine, etc. 20KG/cardboard barrel, light-proof, sealed, stored in a cool and dry place.
Application performance
PVPP products are insoluble high molecular cross-linked polymers with unique network performance structure, which makes up for the application defects that are limited in some aspects due to the excellent solubility of PVP. And PVPP is insoluble in acid, alkali and general organic solvents, while PVP is the opposite. PVPP has good physiological safety, water absorption, water insolubility, complexation and other excellent properties, and has broad application prospects in the fields of medicine, food, daily chemical industry, feed, etc.
Biomedicine field: PVPP has good physiological inertness and biocompatibility, as well as good comprehensive performance. PVPP can be used for drug disintegrants, drug sustained-release carriers and hemodialysis membranes. Due to the water absorption and expansion of cross-linked PVPP, a high pressure is created in the tablet (capsule), which quickly disintegrates into countless small particles, improving the bioavailability of the human body. The drug controlled release system based on various polymer biomaterials improves the continuity and specificity of the drug effect. PVPP has a good ability to absorb liquids, can shield bacteria through the air, can absorb and release drugs, so it can also be used as a wound dressing.
Brewing and beverage industry: PVPP has strong selective adsorption ability and can effectively remove anthocyanins and polyphenols in plant-based beverages, thereby removing non-biological precipitation in plant-based beverages, maintaining taste and original flavor, improving clarity, improving color, and extending shelf life. Therefore, it is used in beer, juice, beverage, wine and other industries.
Company Profile
Yuking Technologies is a high-tech enterprise featuring water-soluble polymers with global vision, core competitiveness and industry discourse right.
The company was founded in 2005 with headquarters and R&D center located in Shanghai Zhangjiang International Medical Zone and its pilot &manufacturing bases respectively located in Shanghai Lingang New Area and High-tech district in Hubei Xiangyang.
Our factory has passed the ISO 9001 quality management system, ISO 14001 environmental management system, EXCiPACT, CEP, HALAL, KOSHER certifications and the US FDA registration(DMF), and has obtained the relelvant Drug Manufacturing License.
Yuang Technology will adhere to the business philosophy of "meeting customer needs,pursuing excellent quality,building an excellent team, fulfilling social responsibility",stick to scientific and technological innovation, and continue to
provide customers with quality products and services.
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