Crospovidone XL\XL10\SF, PVPP Type A/B

Category:Excipients > Disintegrants > Tablet Disintegrants
Product Name:Crospovidone XL\XL10\SF, PVPP Type A/B
CAS No.:25249-54-1/9003-39-8
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):Negotiable
Company:SHANGHAI YUKING WATER SOLUBLE MATERIAL TECH CO., LTD

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: No.101,Guanyu Road,Hi-Tech District,Xiangyang,Hubei(factory)

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 5000kg

    Packaging Information: 20kg/drum

  • Delivery Lead Time: Negotiable

    Sample Provided: yes

    Payment Terms: T/T

    Product description:

    Crospovidone is a white or nearly white, hygroscopic and easy-flowing powder, odorless or slightly odorous, insoluble in water, alkali, acid and common organic solvents, with strong swelling properties and complexing ability with many types of substances.

    Pharmacopoeia name: Crospovidone, Crospovidonum (USP), Crospovidone (EP)

    Chemical name: Cross-linked polyvinyl pyrrolidone

    INCI/CTFA:Insoluble PVP

    CAS number:9003-39-8、25249-54-1

    Main properties: This product has a high capillary/water content, large specific surface area, extremely strong hydration ability, high and rapid water absorption, strong water absorption and swelling ability, and has the same complexing ability as polyvinyl pyrrolidone, and can complex with a variety of substances, such as phenols, iodine, etc. 20KG/cardboard barrel, light-proof, sealed, stored in a cool and dry place.

    Application performance

    PVPP products are insoluble high molecular cross-linked polymers with unique network performance structure, which makes up for the application defects that are limited in some aspects due to the excellent solubility of PVP. And PVPP is insoluble in acid, alkali and general organic solvents, while PVP is the opposite. PVPP has good physiological safety, water absorption, water insolubility, complexation and other excellent properties, and has broad application prospects in the fields of medicine, food, daily chemical industry, feed, etc.

    Biomedicine field: PVPP has good physiological inertness and biocompatibility, as well as good comprehensive performance. PVPP can be used for drug disintegrants, drug sustained-release carriers and hemodialysis membranes. Due to the water absorption and expansion of cross-linked PVPP, a high pressure is created in the tablet (capsule), which quickly disintegrates into countless small particles, improving the bioavailability of the human body. The drug controlled release system based on various polymer biomaterials improves the continuity and specificity of the drug effect. PVPP has a good ability to absorb liquids, can shield bacteria through the air, can absorb and release drugs, so it can also be used as a wound dressing.

    Brewing and beverage industry: PVPP has strong selective adsorption ability and can effectively remove anthocyanins and polyphenols in plant-based beverages, thereby removing non-biological precipitation in plant-based beverages, maintaining taste and original flavor, improving clarity, improving color, and extending shelf life. Therefore, it is used in beer, juice, beverage, wine and other industries.

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