crospovidone

Cross-linked povidone is a white or off-white free-flowing powder, no special odor, insoluble in water, acid, alkali and commonly used solvents. It can be used as a super disintegrant, because it has strong swelling power in water and does not form a gel after expansion, which can effectively improve the dissolution and bioavailability of drugs, so it is considered to be the preferred disintegrant for high-grade tablets, especially suitable for the formulation of instant and chewable tablets. It can also be used as an adsorbent and complexing agent, because it has very good co-solubility, can be complexed with polyphenols, carboxylic acids, tannins and small molecules, and can stabilize the active ingredients of drugs through complexation, and improve drug release and bioavailability. It can also be used as a suspension stabilizer to reduce the sedimentation of drug particles and increase the redispersion capacity of sedimented liquids.