Crospovidone

Chemical Name

Crospovidone 

CAS No.

25249-54-1

Molecular Formula

Molecular Weight

111.1418

Molecular Structure

Storage

Keep in well-closed container, protected from light

Usage

Extra and Intra granular super disintegrant for tablets,

Granules and hard gelatin capsules

Stablizer for oral and topical suspensions

Dissolution enhancer and impoves bioavailability, Filtration acid 

ITEMS

XL

XL-10

Appearance

White or yellowish-white, hygroscopic   powder

Identification A,B,C

Pass

Identification D

A

B

Solubility

Parctically insoluble in water, ethanol 96% and   methylene chloride

Water soluble substances

≤1.5%

≤1.5%

Loss on Drying

≤5.0%

≤5.0%

Vinylpyrrolidine 

≤10ppm

≤10ppm

Peroxides

≤400ppm

≤1000ppm

Nitrogen Content

11.0-12.8%

11.0-12.8%

Heavy Metals

≤10ppm

≤10ppm

Sulphated Ash

≤0.1%

≤0.1%

Particle Size

40-120um

20-40um

Hydration Capacity

3-9

3-9

Powder Flow

Positive

Setting Volume

≥60ml

Total Aerobic Plate Count

≤100CFU/g

Total Mold/Yeast Count

≤100CFU/g

Standard

Latest USP, EP & JP