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Clarithromycin/CAS No.:81103-11-9
1.CAS NO.:81103-11-9
2.Color:white powder
3.Standard:usp
4.paking:25kg/drum
5. Appearance: White or almost white crystalline powder , No odor and bitter.Insoluble in water, freely soluble in chloroform, soluble in acetone or ethyl acetate, sparingly soluble in methanol of alcohol.
6. indications:
Mainly used for caused by sensitive bacteria upper and lower respiratory tract, including tonsil inflammation, sore throat, deputy sinusitis, bronchitis, pneumonia, etc, skin, soft tissue infection, pus furuncle, erysipelas, folliculitis, wound infection and so on, curative effect and other large ring lactone class similar. The goods can also be used to chlamydia trachomatis or dissolved ureaplasma urealyticum reproduction caused by urinary tract infection, AIDS patients with atypical mycobacteria infection.
Appearance
White or almost white crystalline powder, No odor and bitter.Insoluble in water, freely soluble in chloroform, soluble in acetone or ethyl acetate, sparingly soluble in methanol of alcohol.
Conforms
Identification Tests (IR)
Conforms to the reference spectrum
Conforms
Specific optical rotation
-89°-95°
-92°
Crystallinity
Should conform to requirements
Conforms
PH
Between 7.5 and 10.0
8.8
Water
≤2.0%
0.72%
Residue on ignition
≤0.3%
0.04%
Residual Solvents
Ethanol≤0.5%
Not detected
Heavy metals
≤20ppm
<20ppm
Assay (HPLC, dried substance)
9601040ug/mg
981ug/mg
Conclusion: Conforms to USP 28 specification for Clarithromycin