Chymotrypsinogen

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Chymotrypsinogen
CAS No.:9035-75-0
Standard:ChP, USP, BP, EP, JP
Price(USD):0.00
Company:BEIJING GEYUANTIANRUN BIO-TECH CO.,LTD.

Basic Info
  • Grade: food grade, pharmaceutical grade, injection grade, veterinary use, etc.

    Factory Location: China Beijing Beijing

    Main Sales Markets: North America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Sample Provided: no

    Payment Terms: TT 、LC

    Source: Bovine (Porcine) pancreas

    General description

    Chymotryupsin is white and light yellow crystal or amorphous powder, and easily soluble in the water, but insoluble in organic solvent. Relative molecular mass is 24000, and the optimum PH is 8~9. It is stable at a dry state, but will be quickly deactivated in water solution, most stable in the water solution with PH3~4. When it acts on the protein, it will hydrolyze the peptide bond formed by the carboxyl of L-tyrosine and L-phenylalanine in priority.

    The high purity Chymotrypsin of Beijing Geyuantianrun Bio-tech Co., Ltd.. is purified by re-crystallization, and then by Ion Exchange Chromatography and ultra-filtration.

    Application

    Ø  In the clinical, it always used to general trauma, wound healing that after surgery, anti-inflammatory, prevent local edema, hematocele, sprain hematoma, partial swelling that after breast surgery, tympanitis, rhinitis and so on. Use for the removal of cataract, Loose the lashes muscle ligament, reduce the cyst rupture and the hurt of retina.Besides, the combination use with the Trypsin and used as a broad-spectrum anti-inflammatory drugs.

    Ø  as the auxiliary medicine of antibiotic and antifungal drugs,it is widely used in  the field of animal medicine and animal health industry.

     

    Specification

    Items

    Specification

    Standard

    Appearance

    White or almost white lyophilized powder

    USP37

    Identification

     No purple color develops within 3 minutes

    USP37

    Loss on drying

    No more than 5.0%

    USP37

    Residue on Ignition

    No more than 2.5%

    USP37

    Microbial limits:

    Pseudomonas aeruginosa

    Salmonella

    Staphylococcus aureus

    Absent

    USP37

    Trypsin

    No more than 1%

    USP37

    Assay

    Chymotrypsin≥1000 USP units/mg powder

    USP37

     

     

     

    Items

    Specification

    Standard

    Description

    White crystalline lyophilized powder

    EP8.0

    Identification

    A) A purple colour develops

     B)No purple colour develops within 3 min of mixing

    EP8.0

    Appearance of solution

    Solution S is not more opalescent than

    reference suspension Ⅱ

    EP8.0

    Absorbance

    1) 281nm : 18.5 ~ 22.5

    2) 250nm : not more than 8.0

    EP8.0

    PH

    3.0-5.0

    EP8.0

    Histamine

    Not more than 1µg/5.0µkatal

    EP8.0

    Loss on drying

    Not more than 5%

    EP8.0

    Limit of trypsin

    Not more than 1%

    EP8.0

    Microbial limits:

    Pseudomonas aeruginosa

    Salmonella

    Absent

    EP8.0

    Assay

    Not less than 5.0 ukatal/mg, calculated on the dried basis

    EP8.0

    Storage

     Sealed, Dark, at temperature 2-8℃

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