Cephradine compacted/micro

Category:Active Pharmaceutical Ingredients > Antibiotics > Cephalosporins
Product Name:Cephradine compacted/micro
CAS No.:38821-53-3
Standard:ChP, USP, BP
Price(USD):1~10
Company:Arshine Group Co.,Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Block 14, No.100, Luyun Road, Changsha 410205, Hunan, China.

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/C

    Welcome to the world of advanced antibiotic therapy with Cephradine, a trusted and potent medication designed to combat bacterial infections effectively. With its broad spectrum of action and proven track record, Cephradine stands as a reliable choice for healthcare providers and patients alike. Embrace the power of Cephradine to restore health and vitality in the face of bacterial challenges.

    What is Cephradine?

    Cephradine belongs to the class of first-generation cephalosporin antibiotics. It is formulated to target a wide range of bacterial pathogens responsible for various infections. As a beta-lactam antibiotic, Cephradine disrupts bacterial cell wall synthesis, leading to the eventual death of the harmful bacteria.

    How Does Cephradine Work?

    Cephradine's mode of action involves inhibiting the enzymes responsible for building bacterial cell walls. By doing so, it weakens the integrity of the cell wall, causing it to rupture and leading to the destruction of the bacteria. This mechanism ensures a rapid and effective response to bacterial infections.

    Key Features and Benefits:

    1:Broad-Spectrum Activity: Cephradine showcases excellent efficacy against both Gram-positive and Gram-negative bacteria, making it a versatile solution for a wide range of infections.

    2:Respiratory Infections: Cephradine is particularly effective in treating respiratory infections, including bronchitis, tonsillitis, and sinusitis, offering relief from troublesome symptoms.

    3:Urinary Tract Infections (UTIs): Cephradine helps combat UTIs caused by susceptible bacteria, promoting quick recovery and reducing the risk of complications.

    4:Skin and Soft Tissue Infections: From mild to moderate skin infections, Cephradine targets bacteria responsible for cellulitis, wound infections, and other skin-related concerns.

    5:Surgical Prophylaxis: Cephradine is widely used as a prophylactic measure before certain surgical procedures to prevent potential infections.

    Product Name:

    Cefradine

    Batch No:

    32051704082

    Manuf Date:

    20 April 2017

    LAB Record No.

    BPAC04-1704005

    Specification:

    BP2014

    Package Size:

    25kg/drum

    Batch Size:

    857.21Kg

    Report Date

    03 May 2017

    Retest Date:

    March 2020

    PARAMETER

    SPECIFICATIONS

    RESULTS

    Anpearance

     

    white or slightly yellow,

     hygroscopic powder

     

    Complies

    Identification

     

    The IR spectrum confirm to 

    that of reference standard

     

    Complies

     

     

    Appearance of solution

     

    less opalescent than 

    reference suspension II

     

    <reference suspension I

     

    The absorbance at 450 nm 

    is not greater than 0.60

    0.02

     

    pH

    3.5~6.0

    5.1

     

    Specific optical rotation

    +80.0°~+90.0°

    +84.9°

     

     

     

    Related substances

    (D-dihydrophenylgcine 

    NMT 0.25%)

    0.01%

    (Impurity A NMT 0.25%)

    N.D.

    (Impurity C NMT 0.25%)

    0.04%

    Cmpurity D NMT 0.25%)

    0.05%

    (Impurity E NMT 0.25%)

    0.03%

    (Impurity F NMT 0.25%)

    N.D.

    (Impurity G NMT 0.25%)

    N.D.

    (Any other impurity NMT 0.25%)

    0.08%

    (Total impurities NMT 2.0%)

    0.38%

     

    N,N-Dimethylformamide

     

    NMT  0.088%

    N.D.

     

    Acetone

     

    NMT  0.5%

    0.008%

     

    Methylene chloride

     

    NMT   0.06%

    0.009%

     

    Water Content

     

    NMT  6.0%

    4.1%

     

    Sulfated ash

     

    NMT  0.2%

    <0.1%

     

     

     

     

    Assay

     

    cefradine : minimum 90.0 per cent

    (anhydrous substance)

    97.8%

     

    cefalexin: maximum 5.0 per cent

    (anhydrous substance)

    1.2%

     

    4'.5-dihydrocefradine: maximum 

    2.0 per cent(anhydrous substance)

    0.8%

     

    sum of the percentage contents of 

    cefradine, cefalexin and 4',5'- 

    dihydrocefradine :96.0 per cent 

    to 102.0 per cent(anhydrous 

    substance)

    99.8%

    Bulk Density

    For Information only

    0.60g/ml

    Tapped Density

    For Information only

    0.87g/ml

    Remarks:

    N,N-Dimethylaniline in this process is not utilized  2 0     H

    Conclusion

     

    The product complies with specification BP2014.

     

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