Cephalomannine/Harringtonine/Chinese Yew Extract

Product Name

                                        Chinese Yew Extract

Supplier

Xi'an Haoxuan Bio-technology Co., Ltd

Part of used

Bark

Test Method

Active ingredient

Paclitaxel

Specs Available

Odor

Characteristic

Appearance

White crystalline powder

CAS NO.

71610-00-9

Molecular Weight

Molecular Formula

C47H51NO14

Constitutional Formula

Sulphated Ash

<3.0%

Loss on drying 

<3.0% 

Total Plate Count

<1000cfu/g 

Yeast&Mold 

<100cfu/g

E.Coli

Negative

S.Aureus

Negative  

Salmonella

Negative

Pesticides

Negative

Main Function

1.Used to treat patients with lung, ovarian, breast advanced forms of Kaposi's sarcoma.
2.Used for the prevention of restenosis.

Description

Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it 'taxol'. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to 'paclitaxel' and the BMS compound is sold under the trademark 'TAXOL'. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent.

Shelf life

2 years

Package

25kg/drum

Storage

Store in cool and dry places. Keep away from strong light.