Centella Asiatica Extract

About The Detailed Introduction Of Centella Asiatica Extract?

Centella asiatica extract powder contains a variety of triterpenes, including α-amyrinol structure. The main ingredients are madecassoside and madecassoside, which are brown to white fine powder in appearance and slightly bitter in taste. It has excellent effects on treating damp-heat jaundice, heatstroke and diarrhea, sand and blood, carbuncles and sores, and injuries from falls.
Centella asiatica has a medicinal history of more than 2,000 years in my country. Many other countries and regions, such as Madagascar, South Africa, India, Southeast Asian countries and South America, also use Centella asiatica as a brain tonic, diuretic and treatment for leprosy and ulcers. Auxiliary medicines and dermatological medicines. Centella asiatica is listed in the pharmacopoeias of China, France, Spain, Mexico, India, the Netherlands, Venezuela and other countries. Centella asiatica extract is the whole plant of Centella asiatica (L.) Urb. of the Umbelliferae family. Commercial extracts are usually standardized to contain 9% asiatic acid. Note: Centella asiatica standard extract specifications: asiatic acid 29% ~ 30%, asiaticoside 40%, madecassoside 29% ~ 30%, madecassoside 1% ~ 2%.

Extraction Method

1. Extraction And Separation Test Of Centella Asiatica Total Glycosides
Centella asiatica (whole plant) is extracted with 75% ethanol. The extract is passed through the liquid and concentrated under reduced pressure until there is no alcohol smell. Extract with a little petroleum ether to remove the chlorophyll. The concentrated liquid is passed through macroporous resin, first washed with a small amount of water, and then washed with 50% Elute with ethanol, concentrate the eluate, and dry under vacuum. Dissolve the dried product with a little distilled water. Use concentrated hydrochloric acid to adjust the pH to 3 to 4. Precipitate some weakly acidic substances. Add chloroform for extraction to remove fat-soluble impurities. Add concentrated ammonia to adjust the pH to 3 to 4. 6 to 7, and then extract three times with water-saturated n-butanol. The extract Chemicalbook is recovered under reduced pressure until it is nearly dry, then a little 95% alcohol is added to dissolve it, and the refined product is obtained by low-temperature vacuum drying. The content measured by residual iodometric method is above 93%.
2.Production Process Of Centella Asiatica Extract (9%)
Crush the medicinal materials into coarse powder, use 70% alcohol to reflux and extract, separate the extract, recover the ethanol under reduced pressure until all the ethanol is used up, centrifuge the concentrated solution, and concentrate the centrifuged solution under reduced pressure to 12 to 15 Baume (thermal test), spray After drying, the finished Centella asiatica extract is obtained. The Centella asiatica extract produced by this process contains 9% to 10% of total triterpenoid compounds, and the yield is about 20%. 

What Are The Benefits?

1. Anti-Gastric Ulcer Effect
Centella asiatica extract powder can increase the level of γ-aminobutyric acid (GABA) in the brain of gastric ulcer model rats, and can also reduce gastric acid secretion and pepsin activity, showing good anti-ulcer effects.
2. Enhance Memory Function
Centella asiatica aqueous extract can significantly improve the memory of rats in the passive avoidance response test.
3. Effect On The Central Nervous System
Centella asiatica extract has strong central nervous system inhibitory and cholinomimetic effects.
4. Antibacterial Effect
Centella asiatica water extract has antibacterial and antiviral effects, and has inhibitory effects on Pseudomonas aeruginosa, Proteus and Staphylococcus aureus. In addition, asiaticoside can dissolve the wax film of bacteria.
5. Stimulate Biosynthesis
The total triterpenoid extract of Centella asiatica can significantly affect cell proliferation and the biosynthesis of proteins and proteoglycans, significantly increasing collagen and fibronectin.
6. Effect On Skin Tissue
It can accelerate wound healing, promote skin growth, increase local leukocytes, proliferate the connective tissue vascular network, and increase mucus secretion.
7.Other Functions
The crude extract of Centella asiatica was administered orally to female mice and showed significant and lasting activity in reducing fertility; reducing systolic blood pressure and heart rate; and having anti-viral, anti-tension, and anti-stress effects.
8 Anti-Aging
Centella asiatica extract can promote the synthesis of collagen I and III, and can also promote the secretion of mucopolysaccharides (such as the synthesis of sodium hyaluronate), increase the moisture retention of the skin, and activate and renew skin cells. Centella asiatica extract also has the activation effect of fibroblast genes, which can enhance the vitality of skin basal layer cells, maintain skin elasticity and firmness, and smooth fine wrinkles on the face.
9 Anti-Inflammatory Activity
The terpenoids in Centella asiatica extract can significantly increase the content of collagen and cell layer fibronectin (fibronectin is widely involved in cell migration, adhesion, proliferation, hemostasis and skin tissue repair, etc.), and can stimulate and promote scarring. The production of mature type I collagen reduces the generation of inflammatory responses. In addition, Centella asiatica extract can also reduce the production of pro-inflammatory mediators (IL-1, MMP-1), improve and repair the skin's own barrier function.
10 Moisturizing Actives
It is related to the triterpene saponin compounds in Centella asiatica extract. Centella asiatica triterpene saponin is a hydrophilic sugar chain, mainly glucose and rhamnose, which can combine with water in the occlusive layer to improve the epidermal barrier ability. Enhances skin moisture.

What Are The Application Directions?

Pharmaceutical Field:
Centella asiatica extract powder is widely used in the pharmaceutical field. It contains a variety of active ingredients, such as asiaticoside, flavonoids, etc., which have antibacterial, anti-inflammatory, antioxidant and other effects. Centella asiatica extract is often used in the manufacture of topical skin ointments, sprays, etc. to treat various skin diseases, such as eczema, acne, burns, etc. It can relieve skin inflammation, promote wound healing, calm and soothe the skin, etc.

Cosmetics Field:
It is also widely used in the field of cosmetics. Due to its antioxidant, anti-inflammatory, moisturizing and other properties, Centella asiatica extract is often added to skin care products, such as facial masks, lotions, essences, etc. It can help improve skin texture, soothe sensitive skin, and reduce problems like breakouts and inflammation. Centella asiatica extract is also used as an ingredient in sunscreen products to protect the skin from UV rays.

Oral Care Field:
It can also be used in oral care products. It has antibacterial, anti-inflammatory, hemostatic and other effects, and can be used to make toothpaste, mouthwash and other products. Centella asiatica extract can inhibit the growth of oral bacteria, prevent dental caries and oral inflammation, and can also reduce oral odor.

Other Apps:
There are other applications as well. For example, in the food industry, Centella asiatica extract can be used as an additive for natural pigments and flavors to give food a certain color and aroma. In addition, Centella asiatica extract can also be used in the agricultural field as a plant growth regulator to promote plant growth and development.

Company Introduction And Certificates Obtained

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Centella asiatica extract powder etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA,  and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

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