Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Block 14, No.100, Luyun Road, Changsha 410205, Hunan, China.

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/C

    Brimonidine L-tartrate is a pharmaceutical compound used primarily in ophthalmic solutions to treat conditions like glaucoma and ocular hypertension. It falls under the category of alpha-adrenergic agonists and works by decreasing the fluid production in the eye, thereby reducing intraocular pressure.

    A typical product description for Brimonidine L-tartrate powder might include:

    1. Chemical Name: Brimonidine L-tartrate
    2. Chemical Formula: C11H10BrN5.C4H6O6
    3. Appearance: White to off-white crystalline powder
    4. Solubility: Soluble in water and sparingly soluble in alcohol.
    5. Pharmacological Action: Acts as an alpha-adrenergic agonist, selectively binding to alpha receptors in the eye, thereby reducing intraocular pressure by decreasing aqueous humor production and increasing uveoscleral outflow.
    6. Medical Uses: Formulated into ophthalmic solutions for the treatment of glaucoma and ocular hypertension.
    7. Dosage Forms: Typically available in the form of eye drops or ophthalmic solutions.
    8. Dosage and Administration: The dosage and frequency of administration depend on the severity of the condition and the doctor's prescription. Usually, it's applied topically to the affected eye(s) as directed.
    9. Safety and Precautions: While generally safe, Brimonidine L-tartrate may cause side effects such as ocular irritation, dry mouth, fatigue, or changes in blood pressure. It should be used cautiously, especially in patients with cardiovascular diseases or depression.
    10. Storage: It should be stored in a dry place at room temperature, away from light and moisture.

    As with any medication, it's crucial to use Brimonidine L-tartrate as prescribed by a healthcare professional to avoid potential adverse effects and to maximize its therapeutic benefits for the specific eye condition being treated.

    Product Name

    Brimonidine Tartrate

    CAS No.

    70359-46-5

    Production Date

    Mar.09,2022

    Report Date

    Mar.14,2022

    Batch No

    IFP07-220301

    Retest Date

    Mar.08,2024

    Quantity

    10.3Kg

    Packing

    1kg/Alu

    minium 

    bag

     

    ITEMS

    SPECIFICATION

    RESULTS

    Appearance

    White or slightly yellowish or slightly brownish powder

    Conforms

    Identification

    A:Specific optical rotation

    B:Infrared absorption spectrophotometry

    Conforms

    Conforms

    Solubility

    Soluble in water,practically insoluble in anhydrous ethanol and in toluene

    Conforms

    Loss on Drying

    ≤0.50%

    0.25%

    Heavy Metals

    ≤20ppm

    Conforms

    Sulfated Ash

    ≤0.20%

    0.09%

    Specific Optical Rotation

    +9.0°  -  +10.5°

    +9.8°

     

    Residual Solvents

    Bromobenzene≤290ppm

    Acetone≤3000ppm

    Conforms

    Conforms

     

     

     

     

     

    Related Substances

    Specified impurities:

    N-(imidazolidin2ylidene)quinoxalin-6-amine≤0.1% 5-bromoquinoxalin-6-amine≤0.1%

    Quinoxalin-6-amine≤0.1%

    1-(5-bromoquinoxalin-6-yl)thiourea≤0.1%

    2-(5-bromoquinoxalin6yl)guanidine≤0.1%

    5-bromo-N-(1H-imidazol-2-yl)Quinoxalin-6-amine≤0.1% -(2-aminoethyl)-3-(5-bromoquinoxalin-6-yl)urea≤0.19 Unspecified impurities≤0.1%

    Total≤0.2%

     

    Conforms

    Conforms

    Conforms

    Conforms

    Conforms

    Conforms

    Conforms

    Conforms

    0.14%

    Assay(On Dried 

    Basis)

    99.0%-101.0%

    100.1%

    Packaging and Storage

    Preserve in tight containers,protected from light

    Conclusion

    The product complies with BP2015 Standard

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