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Main Sales Markets: orth America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no
Generic name: Vinpocetine Glucose Injection
Properties
This product is a colorless or almost colorless clear liquid.
Pharmacology and Toxicology
Pharmacological effects: This product is a cerebral vasodilator, which can inhibit the activity of phosphodiesterase, increase the effect of vascular smooth muscle relaxation messenger C-GMP, and selectively increase cerebral blood flow. In addition, it can inhibit platelet aggregation and reduce human blood viscosity. Enhance red blood cell deformability, improve blood fluidity and microcirculation, promote brain tissue uptake of glucose, increase brain oxygen consumption, and improve brain metabolism.
Pharmacokinetics
This product is widely distributed in the body and eliminated quickly from plasma. It can enter the brain tissue through the blood-brain barrier. The concentration in cerebrospinal fluid is 1/30 of the blood concentration; it can enter the placenta. The binding rate to human plasma protein is 66%. The main metabolite of the liver is apovininine, which is excreted by the kidneys. Its pharmacological effects are similar to those of the prototype drug, but the efficacy is lower. This product has no tendency to accumulate in the body.
Indications
Improve various symptoms induced by cerebral infarction sequelae, cerebral hemorrhage sequelae, cerebral arteriosclerosis, etc.
Dosage
Intravenous drip. The initial dose is 20 mg per day, and can be increased to 30 mg per day according to the condition of the disease, instilled slowly, or as directed by a doctor.
Adverse reactions
Allergies: Sometimes skin rashes may occur, and occasionally allergic symptoms such as measles, itching, etc. should be discontinued if this symptom occurs.
Mental nervous system: Sometimes headache, dizziness, occasionally drowsiness, numbness in the side limbs, and increased weakness.
Digestive tract: Sometimes nausea, vomiting, and occasionally symptoms such as loss of appetite, abdominal pain, and diarrhea.
Circulatory organs: Sometimes facial flushing, dizziness and other symptoms may occur.
Blood: Leukopenia may sometimes occur.
Liver: Sometimes AST, ALT, r-GT, LDH and AL-P may be elevated, and occasionally jaundice may be seen.
Kidney: occasionally increased blood urea nitrogen.
Occasionally feeling of burnout
Taboo
1. Those who are allergic to any ingredient in this product are prohibited;
2. It is forbidden for patients with acute intracranial hemorrhage;
3. Those with severe ischemic heart disease and severe arrhythmia are prohibited.
4. Pregnant women or women who may be pregnant are contraindicated.
Precautions
1. It should be used under the guidance of a doctor.
2. When allergic symptoms appear, stop the medication and seek medical treatment immediately.
3. Women who are breastfeeding should avoid using this product. If they have to use it, they should stop breastfeeding.
4. This product should not be used in combination with heparin.
5. For long-term use, attention should be paid to blood changes.
6. This product cannot be injected intravenously or intramuscularly.
[Medicine for pregnant and lactating women]
It is contraindicated for pregnant women or women who may be pregnant.
Breastfeeding women should avoid using it, and stop breastfeeding when it must be used.
[Children's medication] There is still a lack of research and reports on the safety and effectiveness of this product for children's medication.
[Medication for elderly patients] See [Usage and Dosage] or follow the doctor's advice.
[Drug interaction] This product cannot be used simultaneously with heparin.
OverdoseLack of this product
Audited Supplier
Pharma Sources Insight June 2024: Globalization on the Go
