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Category:Active Pharmaceutical Ingredients
Product Name:Biotin
CAS No.:58-85-5
Standard:USP, BP, EP, JP
Price(USD):0.00
Company:WELLGREEN TECHNOLOGY CO.,LTD
Grade: Pharmaceutical grade&Nutritional grade
Factory Location: Shaanxi Province
Main Sales Markets: North America,Western Europe,Eastern Europe,Australasia,Asia,Middle East
Monthly Production Capacity: 5000KG
Packaging Information: 20KG/Carton
Delivery Lead Time: Immediately
Sample Provided: yes
Payment Terms: T/T,Western Union,Paypal
D-Biotin (Vitamin H Biotin)
Biotin is also called D-Biotin or vitamin H or vitamin B7.Biotin supplements are often recommended as a natural product to counteract the problem of hair loss in both children and adults.Increasing dietary biotin has been known to improve seborrheic dermatitis.Diabetics may also benefit from biotin supplementation.
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Name:D-Biotin
Other Names:Vitamin H Biotin vitamin B7
CAS:58-85-5
MF:C10H16N2O3S
MW:244.31
EINECS:200-399-3
Specification: 1% 2% 99%
Appearance: White fine powder
Solubility in water: Slightly soluble (Insoluble in organic solvents)
Ref Standard: EP7.0&USP35
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Application
1.Biotin is a member of the B complex family, called also vitamin H, coenzyme
2.It is a kind of water-soluble Vitamin, acts as a coenzyme during the metabolism of protein, fats, and carbohydrates, maintaining healthy skin and hair, and as necessary material for growth, digestion, and muscle function.
3.D-Biotin is white or whitish crystal powder or colorless crystal. D-Biotin solves in hot water or diluted alkali solution. D-Biotin slightly solves in water or ethanol, but hardly solve in acctone. D-Biotin is white to off-white powder, good fluidity, hygroscopic.
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Main Function:
1. With the prevention of skin diseases, and promote lipid metabolism and other physiological functions. HEALTH protein can lead to extensive use of biotin deficiency, which causes loss of hair, dermatitis, weight loss and death.
2. Biotin of every trace of living cells contain growth factors, is the fat metabolism and other important reversible carboxylation reaction and the formation of carboxyl transfer of carbon dioxide plays an important role in the maintenance of normal growth and development, to keep the skin and bone marrow Indispensable health.
3.Coenzyme biotin transporter from the role of carbon dioxide, it is necessary for fat and carbohydrate metabolism.
4.To prevent the hair on bald have a preventive treatment of disease.
5.Relieve muscle pain.
6.It is necessary for the synthesis of vitamin C substances.
7.Biotin and vitamin B2, B6, A, nicotinic acid has a complementary role, helping fat metabolism, can keep the skin healthy.
8.Promote the sweat glands, spiritual organizations, bone marrow, male gonads, skin and hair of normal operation and growth
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COA
Items & Results |
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Item |
Spec. |
Result |
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Appearance |
White off-white powder |
Conforms |
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Specific rotation |
+89°~ +93° |
+90.77° |
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Residual solvents |
Chloroform:≤ 6ppm Pyridine:≤ 20ppm Ethanol:≤ 500ppm |
0.01ppm 0.01ppm 20ppm |
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Melting range |
229~233°C |
229.7-230.4°C |
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Loss on drying |
≤1.0% |
0.19% |
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Bulk density |
~0.3g/cm³ |
Conforms |
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Sulfate ash |
≤ 0.1% |
0.016% |
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Heavy metal |
Pb: ≤0.5ppm As: ≤1ppm Cd: ≤1ppm Hg: ≤0.1ppm |
0.05ppm 0.5ppm 0.01ppm 0.006ppm |
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Particle size |
50% min < 10μm 90% min < 20μm 98% min < 30μm |
Conforms |
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Microbial Limit |
Total Plate count: ≤ 1000 cfu/g |
10 cfu/g |
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Fungi & Yeast:≤ 100 cfu/g |
5 cfu/g |
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Salmonelle:Negative |
Negative |
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E. Coli:Negative |
Negative |
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S. Aureus:Negative |
Negative |
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Total Coli:≤50cfu/g |
Negative |
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Solubility |
Very slightly soluble in water |
Conforms |
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Assay |
97.5% ~ 100.5% |
99.4% |
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Storage |
Store in dry and well closed containers |
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Conclusion |
Conform to USP35 standard |
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Analyst |
Ma Liang |
Review |
Liu Aiqin |
Supervisor of QC |
Li Min |
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