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Category:Active Pharmaceutical Ingredients > Vitamin
Product Name:Benfotiamine
CAS No.:245-013-4
Standard:ChP
Price(USD):Negotiable
Company:Hubei Youyou Fushui Biomedical Technology Co., Ltd
Grade: Pharmaceutical Grade
Factory Location: China
Main Sales Markets: Middle East,Africa
Packaging Information: 25kg/drum
Sample Provided: yes
Payment Terms: T/T
Benfotiamine is an amphiphilic S-acyl thiamine derivative. It is a lipid-soluble vitamin B1, which improved the low bioavailability of water-soluble vitamin B1 and increased the concentration of thiamine in blood and tissues, so the therapeutic effect enhanced.
Benfotiamine and Benfotiamine premix also available.
CAS No.: 22457-89-2
EINECS No.: 245-013-4
MF: C19H23N4O6PS
Specification
Item |
Specification |
|
Description |
White crystal or white crystalline powder |
|
Identification |
The retention time of main peak is accordant with that of Benfotiamine RS |
|
Melting Point |
≥198℃ |
|
Loss on drying |
≤1.2% |
|
Clarity and solution color |
Colorless to light yellow clear solution |
|
Chloride |
≤0.053% |
|
Sulphate |
≤0.011% |
|
Heavy metals Cd As Pb Hg |
≤20ppm ≤1ppm ≤1ppm ≤0.5ppm ≤0.3ppm |
|
Bulk density |
≥0.35g/ml |
|
Related substances |
||
Thiamine |
≤0.1% |
|
Benzoic acid |
≤0.1% |
|
Total impurities |
≤1.0% |
|
Assay |
98.0% to 102.0% |
|
Microbe test |
||
Total Plate Count |
≤1000 cfu/g |
|
Yeast & Mold |
≤100 cfu/g |
|
Salmonella |
Negative |
|
E. Coli |
Negative |
|
Staphylococcus Aureus |
Negative |
|
Packing: 25kg/drum
Application
Benfotiamine has been widely appeared on the market of the world, including the United States, Japan and Europe. It has tablets, granules and other forms.
(1) Used for the prevention and treatment of vitamin B1 deficiency;
(2) Used for supplementing when demand for vitamin B1 increased and there is insufficient intake from food (fatigue syndrome, hyperthyroidism, pregnancy, lactation, intense physical labor, etc.);
(3) Used for the treatment of non alcoholic Wernicke encephalopathy;
(4) Used for treating beriberi;
(5) Used for the treatment of diseases speculated to be related to vitamin B1 deficiency and metabolic disorders, such as neuralgia, muscle pain, joint pain, peripheral neuropathy, peripheral nerve paralysis, myocardial metabolic disorders, constipation and other gastrointestinal motility disorders.
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