Antibiotics Polymyxin B

Name: Antibiotics Polymyxin B
Availability: antibiotics-polymyxin-b-19690.html

Category:Active Pharmaceutical Ingredients > Antibiotics > Other Antibiotics
Product Name:Antibiotics Polymyxin B
CAS No.:1405-20-5
Standard:In-house Standards
Price(USD):0.00
Company:Beijing Global Biologicals Co.Ltd

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Basic Info

Grade: Pharmaceutical Grade

Factory Location: Hai dian Beijing china china

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Asia,Africa
Contract Manufacturing: CRO,CMO
Sample Provided: yes

Antibiotics Polymyxin B

Polymyxin B is an antibiotic primarily used for resistant Gram-negative infections. It is derived from the bacterium Bacillus polymyxa. Polymyxin B is a mixture of two closely related compounds, polymyxin B1 and polymyxin B2. It has a bactericidal action against almost all Gram-negative bacilli except the Proteus group. Polymyxins bind to the cell membrane and alter its structure, making it more permeable. The resulting water uptake leads to cell death. Polymyxins are cationic, basic proteins that act like detergents (surfactants). Side effects include neurotoxicity and acute renal tubular necrosis. Polymyxins are used in the topical first-aid preparation Neosporin.

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