Amyloid beta-protein fragment 1-40

Category:Intermediates > Pharmaceutical Intermediates
Product Name:Amyloid beta-protein fragment 1-40
CAS No.:131438-79-4
Standard:In-house Standards
Price(USD):Negotiable
Company:Hangzhou Go Top Peptide Biotech Co.,Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Hangzhou economic development zone no. 6 street 5 b03 high-tech incubator building 1, 452

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/L

    Alzheimer's disease (AD) is a kind of onset conceals the progressive development of the nervous system degenerative disease.
    Clinically to memory impairment, aphasia, disuse, agnosia, depending on the spatial skills damage, executive dysfunction and comprehensive performance for dementia characteristics such as personality and behavior change.
    Epidemiological studies have shown that non-steroidal anti-inflammatory drugs (epoxy) synthase inhibitors can prevent or delay the onset of alzheimer's disease, brain inflammatory before clinical symptoms promote disease progression.
    Beta amyloid protein can cause inflammatory cytokines and microglia activation, this process will release hydrogen peroxide, TNF alpha and beta IL - 1 killer factor.
    Hydrogen peroxide promote microglia proliferation, TNF alpha beta (tumor necrosis factor) and IL - 1 (interleukins) is a very powerful biological activity factor, can quickly kill the pathological changes of neurons.
    And activated inflammatory microglia will exist in alzheimer's patients for a long time of neuritis plaques.
    Experiments found that beta-amyloid, cytokines and activated microglia can strong kill were cultured neurons, compared to beta Amyloid (1-42), beta Amyloid (1-40) has a better solubility in water.
    So, kill microglia activation and prompted the pathological changes of neurons, is likely to be ultimately means for the treatment of such diseases.
    Storage: - 20 ℃ under freeze dry, avoid light preservation remark: used only for research, not for human body

Send your message to this supplier
  • From:
  • To:
    Hangzhou Go Top Peptide Biotech Co.,Ltd.
  • Send a Copy to this Email
  • Message:
    Upload Images / Files
    - Supports jpg, jpeg, png,
     gif, pdf, doc, docx,
     xls, xlsx, txt, rar and zip
    - Max upload 3 files;
     Max  total size: 3MB
    (0/3)

    Enter between 20 to 4,000 characters.This is not what you are looking for ? Post a Sourcing Request Now

  • Verification:
PharmaSources Customer Service