Amyloid β-Protein (5-42) ammonium salt

Category:Intermediates > Pharmaceutical Intermediates
Product Name:Amyloid β-Protein (5-42) ammonium salt
CAS No.:1678415-97-8
Standard:In-house Standards
Price(USD):Negotiable
Company:Hangzhou Go Top Peptide Biotech Co.,Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Hangzhou economic development zone no. 6 street 5 b03 high-tech incubator building 1, 452

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Sample Provided: no

    Payment Terms: L/L

    Humans still stranded Alzheimer's disease (Alzheimer diseases, AD) the two main pathological features: the misfolding of beta amyloid protein (A beta) sedimentary formation of the amyloid plaques in the brain and Tau protein phosphorylation cause nerve fiber entanglement.
    In beta Amyloid Protein (A beta) in the process of continuous research, many fragments polypeptide arises at the historic moment, Amyloid beta Protein (5-42) is one of them.
    By 38 amino acid composition of Amyloid beta Protein (5-42), kept most of beta Amyloid Protein (A beta) sequence, shortens the N the former four amino acids: Asp - Ala - Glu - Phe, so can by contrast experiment, the further understanding of amyloid-beta Protein (A beta) mechanism.
    According to the conventional solid phase peptide synthesis, the Amyloid beta Protein (5-42) in the process of production, products will appear similar to objective product polar impurities peptide, the experimental results is bad for the separation and purification of late.
    Therefore, Rio biological fixation through multiple sets of control experiment, further optimize the synthetic process, avoid the formation of peptides, impurity produced Amyloid beta Protein (5-42) products have higher purity, conducive to the separation and purification of late, to get higher yield.
    Storage: - 20 ℃ under freeze dry, avoid light preservation remark: used only for research, not for human body
     

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