Amoxicillin and potassium clavulanate tablets

Component:
Amoxicillin And Clavulanate Potassium Tablet 625mg.

Character:
This product is an oval film sheet with a concave 'AC' on one side and a line. The other side is the smooth surface, after removing the coating appears white or white.

Indications:

Twice a day this product can be used for short-term treatment of infections such as:

Upper respiratory tract infections such as: tonsillitis, sinusitis, otitis media.

Lower respiratory tract infections such as acute and chronic bronchitis. Lobar pneumonia and bronchopneumonia.

Genitourinary tract infection: cystitis, urethritis, pyelonephritis.

Skin and soft tissue infections: furuncle, abscess, cellulitis, trauma infection.

Bone and joint infections: osteomyelitis.

Other infections include infective abortion, pelvic and abdominal infections.

Usage and dosage:

Common dose:

Adults and children over 12 years old:

Mild to moderate infection, 1 tablet twice a day.

Severe infections may be treated beginning with an injection (this injection is described separately) and continuing with oral preparations.

Oral infection (such as periodontal abscess) dosage:

Adults and children over 12 years old: Take 1 tablet twice a day for five days.

Not recommended for children under 12 years of age.

Precautions:

Patients should be carefully asked about their allergy history and whether they are allergic to penicillin, cephalosporins, or other allergens before using Leptin ®.

Severe and occasionally fatal allergic reactions (anaphylactic shock) have been reported in patients treated with penicillin, only in those allergic to penicillin (see contraindications).

There have been some patients with liver function changes after taking this product. Because the clinical significance of this change has not been determined, caution must be exercised in patients with liver insufficiency. Severe and reversible cholestatic jaundice is rarely reported, and the symptoms and symptoms may also appear up to six weeks after withdrawal. Patients with infectious mononucleosis who use amoxicillin tend to develop a measles - like rash. This product should be avoided in patients suspected of infectious mononucleosis.

Long-term use of this product occasionally causes overgrowth of non-sensitive bacteria.

Prothrombin time (increased INR) is abnormally prolonged in rare patients with proleptin ® and oral anticoagulants, so patients receiving anticoagulant therapy should use this product with caution. Oral anticoagulant doses may have to be adjusted to maintain desired anticoagulant levels.

For patients on sodium-restricted diets, the amount of sodium contained in this product should be included in the total sodium intake if a large dose of this product is administered by injection.

For patients with renal impairment, the dosage of this product should be adjusted according to the "dosage of patients with renal insufficiency" in [Usage and dosage].

Crystallinuria is very rare in patients with reduced urine output, especially during parenteral administration. When taking high doses of amoxicillin, it is recommended that patients take adequate fluid intake and ensure adequate urine output to reduce the likelihood of amoxicillin crystallized urine (see [Drug overdose]).

Medication for special population:

Reproductive toxicity tests in animals (rats and mice) showed no teratogenic effects of oral or parenteral administration of this product. In a separate study of preterm birth and premature rupture of membranes (pPROM), an increased risk of necrotizing enterocolitis in neonates has been reported with prophylaxis of Liprotine ®. Use of this product in pregnant women is limited and, as with all medications, should be avoided unless deemed necessary by a physician, especially during the first trimester of pregnancy.

药物相互作用：

This product is not recommended for use in combination with methylsulfonamide, which reduces renal tubule secretion of amoxicillin. The combination of drugs resulted in an increase in amoxicillin concentration and a prolongation of half-life, but did not affect clavulanic acid concentration.