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Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: no
【CAS】No. 26787-78-0
[Properties] White or off-white crystalline powder; slightly bitter taste.
【Pharmacological effects】
Amoxicillin is a semi-synthetic broad-spectrum penicillin. Its antibacterial spectrum and antibacterial activity are basically the same as ampicillin, but its acid resistance is stronger than ampicillin, and its bactericidal effect is stronger and faster than ampicillin, but it cannot be used to treat meningitis. . The half-life is approximately 61.3 minutes. Amoxicillin is stable under acidic conditions, and has a gastrointestinal absorption rate of 90%. It is more rapidly and completely absorbed than ampicillin. Except for its worse effect on Shigella than ampicillin, the other effects are similar.
Amoxicillin has a strong bactericidal effect and has a strong ability to penetrate cell walls. After oral administration, the lactam group in the drug molecule is immediately hydrolyzed to form a peptide bond, which quickly combines with the transpeptidase in the bacteria to inactivate it, cutting off the only way for the bacteria to rely on transpeptidase to synthesize glycopeptides to build cell walls, making the bacteria The cells quickly become spherical and rupture and dissolve. The bacteria eventually swell and die due to the loss of cell walls and the continuous penetration of water. It has powerful bacteriostatic and bactericidal effects on most pathogenic G+ bacteria and G- bacteria (including cocci and bacilli). Among them, Streptococcus pneumoniae, hemolytic Streptococcus and other Streptococcus species, non-penicillinase-producing Staphylococcus aureus, Enterococcus faecalis and other aerobic Gram-positive cocci, Escherichia coli, Proteus mirabilis, Salmonella species, Haemophilus influenzae , Neisseria gonorrhoeae and other aerobic Gram-negative bacteria that do not produce β-lactamase and Helicobacter pylori have good antibacterial activity. Hemodialysis can remove some drugs, but peritoneal dialysis has no effect on removing this product.
Toxicology: Not clear yet
[Storage] Store in a cool, dry place away from light
[Validity period] Two years
[Packaging specifications] 5 kg/aluminum drum × 2 barrels/box 25 kg/barrel
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