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Category:Active Pharmaceutical Ingredients > Respiratory System Drugs
Product Name:Aminophylline
CAS No.:317-34-0
Standard:USP, BP, EP, In-house Standards
Price(USD):Negotiable
Company:Henan huirun Pharmaceutical Co., Ltd.
Grade: Pharmaceutical Grade, veterinary grade
Factory Location: Industrial Cluster Area, Bo'ai County, Jiaozuo City
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Sample Provided: yes
Payment Terms: L/L
Aminophylline
【 CAS NO 】 317-34-0
【 characteristics 】 this product is a white to light yellow granular or powder, has agglomerate, micro ammonia smell, taste bitter; Absorb the oxygen in the air, carbon and decomposed into theophylline, aqueous alkaline reaction. Dissolved in water, slightly soluble in ethanol, almost insoluble in ether.
[pharmacological action] this product is direct relaxation effect on bronchial smooth muscle. Its mechanism of action is inhibition of phosphodiesterase, slow to make cAMP hydrolysis, rise in the organization cAMP/cGMP ratio, and suppression of histamine and slow the release of the allergic reaction substances such as media, promote the catecholamine release, bronchial smooth muscle relaxation; As well as directly relax bronchial smooth muscle function, so as to relieve bronchial smooth muscle spasm, relieve bronchial mucosal hyperemia and edema, play and asthma effect. In addition, this product has weaker cardiac and diuretic effects.
"Limited" used to relieve bronchial asthma and other animals
【 usage and dosage 】 oral: a quantity, each 1 kg weight, ma 5 ~ 10 mg, dogs, cats, 10 ~ 15 mg;
Intramuscular injection, intravenous injection: a quantity, horses, cattle 1 ~ 2 g; Sheep, pigs, 0.25 ~ 0.5 g; 0.05 ~ 0.1 g.
【 notes 】 (1) internal and can cause reactions such as nausea and vomiting.
(2) the static injection or intravenous drip, such as excessive dosage, the concentration is too high or too fast, can be a strong heart and central nervous excitement, so the injection diluted and attention should be paid to control speed and dosage.
(3) injection strong alkaline, can cause swelling, pain, a deep intramuscular injection should be done.
(4) the liver function is low, heart failure with livestock with caution
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