ADC Linker/ NH2-PEG2-C2-Boc 756525-95-8

Category:Intermediates > Pharmaceutical Intermediates
Product Name:ADC Linker/ NH2-PEG2-C2-Boc 756525-95-8
CAS No.:756525-95-8
Standard:ChP
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 10tons/year

    Contract Manufacturing: CRO,CMO

    Packaging Information: 25kg/bag

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/C

    Product Information

     

     

    Product name

    ANH2-PEG2-C2-Boc;

    ADC linker;

    H2N-PEG2-tBu

    CAS No.

    756525-95-8  

    Molecular Formula

    C11H23NO4

    Molecular Weight

    230.304

    Quality Standard

    98% up by HPLC

     

    Usage

     

    What is ADC Linker?

    ADC Linker refers to the linker in ADC (Antibody Drug Conjugate).

    ADC is composed of Linker, Payload and monoclonal antibody (mAb). It combines the advantages of high specificity and targeted ability and strong killing effect, achieving precise and efficient killing of cancer cells, and has become a hot spot in the research and development of anti-cancer drugs. At present, there are mainly two types of ADC Linker in ADC drugs: the cleavable linker and the non-cleavable linker. The cleavable linker is designed to remain stable in the bloodstream and then release the Payload in the cells. Stable ADC drugs can ensure less Payload release before reaching tumor cells, thereby improving safety and limiting dosage. Fmoc-NH-(PEG)8-CH2CH2COOH is one of ADC linkers.

     

    The advantages of Sinoway's ADC linker:

    1) CDMO of Regulatory Starting Materials and Drug Intermediates (avoid the patent).
    2) Products with high purity(etc. single impurity below 0.05%)
    3) Green chemical technology platform used in Biological enzyme-catalyzed reaction, Continuous flow reaction, chiral synthesis, Commercial-scale ozonolysis, etc.
    4) Production sites equipped with professional quality management under GMP guidance and EHS system, we can undertake high temperature and high pressure, low-temperature reactions, and other special reactions, with the qualification for the use of precursor and highly toxic products.
    5) Most cost-saving proposals for our customers with competitive prices in the market. Some successful items we developed for our customers in our technology platform for your reference

     

    Our main ADC linker:

     

    Amino-PEG4-Alcohol  CAS No.: 86770-74-3

    SMCC CAS No.: 64987-85-5

    VAL-CIT-PAB  CAS No.: 159857-79-1

    Fmoc-NH-(PEG)8-CH2CH2COOH  CAS No.: 756526-02-0

     

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