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Email ：PharmaSources@imsinoexpo.com
Whatsapp ：+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East
Monthly Production Capacity: 100kg
Packaging Information: 1kg/bottle
Sample Provided: yes
Payment Terms: L/L
Product Information
Product name
Latanoprost
Molecular Formula
C26H40O5
Molecular Weight
432.59
CAS No.
130209-82-4
Quality Standard
99% up, medical grade
Appearance
Light yellow oil
COA of Latanoporst
TESTS
SPECIFICATIONS
RESULTS
Description
Colorless or light yellow oil
Light yellow oil
Identification
A: IR
B: The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard solution, as obtained in the assay
Complies
Water
NMT 2.0%
0.05%
Optical rotation
+31°～+38°
+35.2°
Residue on ignition
NMT 0.5%
0.05%
Related substances (HPLC)
Isopropyl
Dipheny lphosphorylpentanoate
NMT0.1%
0.06%
Related compound B
NMT0.5%
0.09%
Related compound A
NMT3.5%
N.D
Any unspecified impurity
NMT0.1%
0.06%
Total other impurities
NMT0.5%
0.08%
Related Compound E
NMT0.2%
0.02%
Residue
Solvent
n-Hexane
NMT0.029%
Not detected
Ethanol
NMT0.5%
0.15%
Methanol
NMT0.3%
Not detected
Isopropanol
NMT0.5%
Not detected
Assay
94.0%~102.0%
99.77%
Conclusion: The product complies as per above specification.
Usage
Function of Latanoprost
Latanoprost is a new type of phenyl substituted prostaglandin F2α, which is a selective F2α receptor agonist. It is an inactive substance that can quickly penetrate into the cornea and can be hydrolyzed into active free acids in the cornea and plasma. It can increase the outflow of aqueous humor through the corneal layer, and the amount of medication is small, but promotes the outflow of aqueous humor. This product can also smooth the trabecular meshwork structure of the glaucoma patients that are usually blocked.
Latanoprost is a new class of ocular hypotensive drugs developed in recent years and gradually applied to the clinic. Unlike other anti-glaucoma drugs, this product does not change the flow coefficient of the aqueous humor, the production of aqueous humor, and suprascleral venous pressure, but reduces the intraocular pressure by increasing the waterproofing from the uveal scleral passage and outflow.
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