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Email ：PharmaSources@imsinoexpo.com
Whatsapp ：+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East
Monthly Production Capacity: 1000kg
Packaging Information: 25kg/drum 1kg/bottle
Delivery Lead Time: 7 days after payment
Sample Provided: yes
Payment Terms: L/L
Product Information
Product name
Penciclovir
CAS No.
39809-25-1
Molecular Formula
C10H15N5O3
Molecular Weight
253.117
Quality Standard
99% up, GMP
Appearance
White or pale yellow powder
COA of Penciciovir
ITEMS
SPECIFICATIONS
RESULTS
Appearance
White or pale yellow crystalline powder
Complies
PH
5.5 to 7.5
6.5
Chloride
Not more than 0.015%
Complies
Related substances
Total impurities
Not more than 1.0%
Complies
Loss on drying
Not more than 0.5%
Complies
Residue on ignition
Not more than 0.1%
Complies
Heavy metals
Not more than 0.002%
Complies
Assay
Not less than 99.0%,calculated on dried basis
99.6%
Conclusion
Complies with the specification
Usage
Function of Penciciovir
Penciclovir is a nucleoside antiviral drug, which has inhibitory effect on type I and type II herpes simplex virus in vitro. In virus-infected cells, viral thymidine kinase phosphorylates penciclovir to penciclovir monophosphate, and cell kinase converts penciclovir monophosphate to penciclovir triphosphate. In vitro experiments show that penciclovir triphosphate and deoxyguanosine triphosphate competitively inhibit herpes simplex virus polymerase, thereby selectively inhibiting herpes simplex virus DNA synthesis and inhibition. Therefore, penciclovir is suitable for the treatment of a variety of herpes virus infections. It has the characteristics of low toxicity and high virus sensitivity. Penciclovir has low oral absorption and is often used for topical administration. Famciclovir is a prodrug of penciclovir and is well absorbed orally.
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