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Email :PharmaSources@imsinoexpo.com
Whatsapp :+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East
Monthly Production Capacity: 1000kg
Packaging Information: 25kg/drum 1kg/bottle
Delivery Lead Time: 7 days after payment
Sample Provided: yes
Payment Terms: L/L
Product Information
Product name
Mupirocin
Molecular Formula
C26H44O9
Molecular Weight
500.6222
CAS No.
12650-69-0
Quality Standard
GMP / USP34 / EP6
Appearance
white powder
COA of Mupirocin
ITEMS
SPECIFICATIONS
RESULT
Appearance
A white or off-white powder
Conforms
Identification(A,B)
Positive
Conforms
Specific Optical Rotation
-20°~ -16°
-18°
Impurity C
Not more than 2.5%
1.6%
Individual impurity
Not more than 1.0%
Conforms
Total impurities
Not more than 4.5%
3.5%
Chlorides
Not more than 0.5%
Conforms
PH
3.0~4.5
3.6
Water
Not more than 1.0%
0.1%
Residual Solvents
Ethyl Acetate
Not more than 500 ppm
Not deteced
Isobutyl Acetate
Not more than 5000 ppm
5
Heptane
Not more than 500 ppm
2
Acetone
Not more than 3000 ppm
15
Assay
93.0-102.0%
98.1%
Usage
Mupirocin is a topical antibiotic for external use, which is a substance produced by Pseudomonas fluorescens culture fluid, namely Pseudomonas A. Its antibacterial effect is mainly by reversibly combining with isoleucine transfer RNA synthetase, preventing isoleucine infiltration, and stopping the synthesis of isoleucine-containing protein in cells to play a bactericidal or bacteriostatic role. Mupirocin shows bacteriostatic effect at very low concentration and bactericidal effect at high concentration. Mupirocin is highly sensitive to various Gram-positive cocci related to skin infections, especially Staphylococcus and Streptococcus. It is also effective against resistant Staphylococcus aureus; Neisseria gonorrhoeae has some antibacterial effect; it is not sensitive to most anaerobic bacteria and normal skin flora. The incidence of drug-resistant mutants in vitro is very low.
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