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Email ：PharmaSources@imsinoexpo.com
Whatsapp ：+86-13621645194
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East
Monthly Production Capacity: 1000kg
Packaging Information: 25kg/drum 1kg/bottle
Delivery Lead Time: 7 days after payment
Sample Provided: yes
Payment Terms: L/L
Product Information
Product name
Lenalidomide
CAS No.
191732-72-6
Molecular Formula
C13H13N3O3
Molecular Weight
259.26062
Quality Standard
98% up, Medicine Grade
Appearance
White to light yellow crystalline powder
COA of Lenalidomide
Test Items
Specifications
Results
Appearance
White to light yellow crystalline powder
conforms
Water content
≤ 4.0%
0.021
Residuce on ignition
≤ 0.5%
0.0032
Residual Solvents
Methanol≤ 3000ppm
1400ppm
Acetonitrile≤ 410ppm
not detected
Carbon tetrachloride≤ 4ppm
not detected
Tetrahydrofuran≤ 720ppm
250ppm
Dimethylformamide
320ppm
≤ 550ppm
Related Substance
Single Impurity≤1%
0.004
Total Impurity≤1.5%
0.008
Assay
≥98.0%
0.996
Test Items
Specifications
Results
Appearance
White to light yellow crystalline powder
conforms
Water content
≤ 4.0%
0.021
Residuce on ignition
≤ 0.5%
0.0032
Residual Solvents
Methanol≤ 3000ppm
1400ppm
Acetonitrile≤ 410ppm
not detected
Carbon tetrachloride≤ 4ppm
not detected
Tetrahydrofuran≤ 720ppm
250ppm
Dimethylformamide
320ppm
≤ 550ppm
Related Substance
Single Impurity≤1%
0.004
Total Impurity≤1.5%
0.008
Assay
≥98.0%
99.6%
Usage
Function of Lenalidomide
1. LenalidomideAPI is an anti-tumor drug developed by Celgene biopharmaceutical company. The chemical structure is similar to thalidomide, which has multiple functions such as anti-tumor, immune regulation and anti-angiogenesis.
2. Lenalidomide inhibits the secretion of proinflammatory cytokines and increases the secretion of anti-inflammatory cytokines in peripheral blood monocytes.
3. Lenalidomide can also inhibit the expression of cyclooxygenase 2(cox-2), but it has no effect on cox-1.
4. Lenalidomide besides can be used to treat MDS and MM, for multiple myeloma, leukemia, metastatic renal cell carcinoma, solid tumor, idiopathic generalized the degeneration amylum and with marrow unripe systemic bone marrow fibrosis disease have certain curative effect.
5. Lenalidomide is currently the most effective drug to treat multiple myeloma.
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