98% up by HPLC USP CAPECITABINE 154361-50-9

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:98% up by HPLC USP CAPECITABINE 154361-50-9
CAS No.:154361-50-9
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 25kg/drum 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

     

    Product Information

     

    Product name

    Capecitabine

    Molecular Formula

    C15H22FN3O6

    Molecular Weight

    359.35

    CAS No.

    154361-50-9

    Quality Standard

    USP34, medical grade

    Appearance

    White powder

     

    COA of CAPECITABINE

     

    Items

    Specifications

    Results

    Apperance

    White or off-white crystalline powder

    White crystalline powder

    Identification

    The spectrum of the sample corresponds to that of RS

    Meets the requirements

     

    The retention time of the major peak of the test solution corresponds to that of the RS

    Meets the requirements

    Specific Rotation

    +96.0°~+100.0°

    +98.1°

    Water

    ≤0.3%

    0.01%

    Heavy Metals

    ≤20ppm

    <20ppm

    (as Pb)

    Residue on ignition

    ≤0.1%

    0.02%

    Assay

    98.0%~102.0%

    99.70%

     

     

    Usage

     

    Function of Capecitabine

     

    Capecitabine is rapidly absorbed through the intestinal mucosa after oral administration, and then converted into an inactive intermediate 5'-deoxy-5'fluorocytidine in the liver by carboxylesterase, and then decellularized by the liver and tumor The action of ammonia enzyme is converted into 5'-deoxy-5 'fluorouridine, and finally catalyzed by thymidine phosphorylase into fluorouracil (5-FU) in tumor tissue.

    Clinical studies have shown that the concentration of 5-FU in tumor tissue after oral administration of this product is significantly higher than blood and muscle levels. The curative effect on various animal tumors is significantly higher than that of 5-FU. This product has a synergistic effect with a variety of anti-tumor drugs.

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