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98% up by HPLC GMP Somatostatin Acetate 38916-34-6
Category:Bio Products > Protein/Antigen/Polypeptide > Other Protein Product Name:98% up by HPLC GMP Somatostatin Acetate 38916-34-6 CAS No.:38916-34-6 Standard:In-house Standards Price(USD):Negotiable Company:Sinoway Industrial Co.Ltd.
Specific optical rotation (anhydrous and acetic acid-free substance)
-37° to -47°
-41°
Solubility
freely soluble in water and in acetic acid, practically insoluble in methylene chloride
Conforms
Related substances (HPLC)
Total impurities: NMT 2.0%
Any impurity: NMT 1.0%
1.3%
0.3%
Water (Karl Fischer)
NMT 8.0 %
6.5%
Acetic acid (HPLC)
3.0% to 15.0 %
8.7%
Bacterial endotoxins
< 10IU/mg
Conforms
Assay (anhydrous and acetic acid-free substance)
95.0% to 104.0%
99.34%
Conclusion
Complies with the standard.
Usage
Function of Somatostatin Acetate
Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation through its interaction with G protein.
① It can inhibit the secretion of growth hormone, thyroid stimulating hormone, insulin and glucagon.
②It can inhibit the secretion of gastric acid stimulated by the test meal and 5-peptide gastrin, and can inhibit the release of pepsin and gastrin.
③It can significantly reduce visceral blood flow, reduce portal vein pressure, reduce blood flow and pressure of collateral circulation, and reduce liver blood flow.
④Reduce the secretion of the pancreas and the secretion of the small intestine and gallbladder, reduce enzyme activity, and have a protective effect on pancreatic cells.
⑤ It can affect the absorption and nutritional function of the gastrointestinal tract.
Application of Somatostatin Acetate
Somatostatin Acetate can be used for severe and acute gastric and duodenal ulcer bleeding; acute erosive or hemorrhagic gastritis severe and acute bleeding; prevention of post-pancreatic complications after pancreatic surgery; inhibition of pancreas and Adjuvant treatment for severe secretion of leaky duct after upper small intestine surgery; regulating human differentiated gastric cancer cell lines