Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 10ton/year

    Packaging Information: 25kg/drum; 5kg/bag, 1kg/bag

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Goserelin Acetate

    CAS No.

    145781-92-6

    Molecular Formula

    C59H84N18O14.C2H4O2

    Molecular Weight

    1269.41

    Molecule Structure

    Quality Standard

    98% up by HPLC, EP

    Appearance

    White slightly yellowish powder

     

    COA of Goserelin Acetate

     

    Items

    Specification

    Results

    Appearance

    White slightly yellowish powder

    Conforms

    Appearance of solution

    Clear, colorless to slightly colored solution in water(10mg/ml)

    Conforms

    Purity(HPLC)

    > 98%

    99.3%

    Peptide

    ≥ 80%

     

    Amino acids

    Arg:0.9-1.1

    Leu: 0.9-1.1

    Tyr: 0.9-1.1

    Glu: 0.9-1.1

    Pro: 0.9-1.1

    His: 0.9-1.1

    Ser: 0.9-1.1

    Trp:Detected

    1.08

    1.00

    0.98

    1,06

    1.07

    1.06

    0.97

    Detected

    Specific optical rotation

    -52- -56°([a]20D(c=0.2 water))

    -54.6°

    Related substances (HPLC)

    Total impurities: ≤ 2.5%
    Any impurity: ≤ 1.5%

    0.9%

    0.3%

    Water (Karl Fischer)

    ≤ 10.0 %

    3.8%

    Acetate content (HPLC)

    ≤ 4.5%-15.7%

    10.3%

    Conclusion

    Complies with the standard.

     

    Usage

     

    Function of Goserelin Acetate

     

    Goserelin acetate is an analog of gonadotropin releasing hormone. It can inhibit ovarian function to make premenopausal women reach the level of postmenopausal hormones. At the same time, it can also protect the ovaries and follicles during chemotherapy. It protects the patient's ovaries from chemotherapy damage, restores ovarian function after stopping chemotherapy, and protects fertility. For premenopausal patients, after stopping goserelin acetate sustained-release implants, menstrual and ovarian function can be restored. At the same time, goserelin acetate is also used in prostate cancer to play a role in drug castration.

     

     

    Application of Goserelin Acetate

     

     

    1. Prostate cancer: This product is suitable for prostate cancer that can be treated with hormones.

    2. Breast cancer: suitable for breast cancer in premenopausal and perimenopausal women who can be treated with hormones.

    3. Endometriosis: Relieving symptoms includes reducing pain and reducing the size and number of endometrial damage.

     

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