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Category:Bio Products > Protein/Antigen/Polypeptide > Other Protein Product Name:98% up by HPLC EP Goserelin Acetate 145781-92-6 CAS No.:145781-92-6 Standard:In-house Standards Price(USD):Negotiable Company:Sinoway Industrial Co.Ltd.
Clear, colorless to slightly colored solution in water(10mg/ml)
Conforms
Purity(HPLC)
> 98%
99.3%
Peptide
≥ 80%
Amino acids
Arg:0.9-1.1
Leu: 0.9-1.1
Tyr: 0.9-1.1
Glu: 0.9-1.1
Pro: 0.9-1.1
His: 0.9-1.1
Ser: 0.9-1.1
Trp:Detected
1.08
1.00
0.98
1,06
1.07
1.06
0.97
Detected
Specific optical rotation
-52- -56°([a]20D(c=0.2 water))
-54.6°
Related substances (HPLC)
Total impurities: ≤ 2.5%
Any impurity: ≤ 1.5%
0.9%
0.3%
Water (Karl Fischer)
≤ 10.0 %
3.8%
Acetate content (HPLC)
≤ 4.5%-15.7%
10.3%
Conclusion
Complies with the standard.
Usage
Function of Goserelin Acetate
Goserelin acetate is an analog of gonadotropin releasing hormone. It can inhibit ovarian function to make premenopausal women reach the level of postmenopausal hormones. At the same time, it can also protect the ovaries and follicles during chemotherapy. It protects the patient's ovaries from chemotherapy damage, restores ovarian function after stopping chemotherapy, and protects fertility. For premenopausal patients, after stopping goserelin acetate sustained-release implants, menstrual and ovarian function can be restored. At the same time, goserelin acetate is also used in prostate cancer to play a role in drug castration.
Application of Goserelin Acetate
1. Prostate cancer: This product is suitable for prostate cancer that can be treated with hormones.
2. Breast cancer: suitable for breast cancer in premenopausal and perimenopausal women who can be treated with hormones.
3. Endometriosis: Relieving symptoms includes reducing pain and reducing the size and number of endometrial damage.