98% up by HPLC DMF Eptifibatide Acetate 148031-34-9

Product Information

Product name

Eptifibatide acetate

Sequence

Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2

CAS No.

188627-80-7 (Eptifibatide (net)),

148031-34-9 (Eptifibatide acetate)

Molecular Formula

C35H49N11O9S2

Molecular Weight

832.4

Molecule Structure

Quality Standard

98% up by HPLC, GMP

Appearance

White slightly yellwish powder

COA of Eptifibatide Acetate

Items

Specification

Results

Appearance

White slightly yellwish powder

Conforms

Purity(HPLC)

> 98%

99.57%

Peptide

≥ 80%

Amino acids

Asp:0.85-1.15

Cys:0.75-1.15

Gly:0.85-1.15

Pro: 0.85-1.15

Har: 0.85-1.15

Trp:Present

1.08

1.00

0.98

1,06

1.07

Specific optical rotation

-53- -57°(C=5, 1% Acetic acid)

-55.6°

Solubility

Soluble in water and 1% acetic acid at a concentration of ≥ 1mg/ml to give a clear, colorless solution

Conforms

Related substances (HPLC)

Total impurities: ≤ 1.5%
Any impurity: ≤ 1.0%

0.6%

0.2%

Water (Karl Fischer)

≤ 5.0 %

3.8%

Acetic acid (HPLC)

≤ 10.0%

8.7%

Bacterial endotoxins

< 10EU/mg

Conforms

Mass balance

95.0%-105.%

98.11%

DMF (GC)

≤0.088%

Conforms

can

≤0.041%

Conforms

Conclusion

Complies with the standard.

Usage