98.5% up, EP/USP/BP Metformin Hydrochloride 1115-70-4

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:98.5% up, EP/USP/BP Metformin Hydrochloride 1115-70-4
CAS No.:Metformin Hydrochloride 1115-70-4
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 25kg/drum 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Metformin Hydrochloride; Metformin HCL

    Molecular Formula

    C4H12CIN5

    Molecular Weight

    165.62

    CAS No.

    1115-70-4

    Quality Standard

    98.5% -101.0%, EP/USP/BP Medical Grade

    Appearance

    White powder

     

    COA of Metformin Hydrochloride

     

    Tests

    Specifications

    Results

    Appearance

    White crystal

    White crystal

    Identifications

    IR: complies with reference spectrum <197k>

    Identification test: it meets the requirements of the test for chloride <191>

    Conforms

    Related compounds

    Cyanogunadine (Imp.A)≤0.02%

    Any other impurity≤0.1%

    Total impurities≤0.5%

    0.001%

    0.004%

    0.01%

    Heavy metals

    ≤0..001%<231>

    <0.001%

    Loss on drying

    ≤0.5%<731>

    0.05%

    Residue on ignition

    ≤0.1%<281>

    0.03%

    Residual solvents

    Methanol≤3000ppm

    380ppm

    Assay (on anhydrous basis)

    98.5% ~ 101.0%

    99.8%

    Conclusion: Conforms with USP37

     

    Usage

     

    Function of Metformin Hydrochloride

     

    Metformin hydrochloride is a hypoglycemic drug, which is commonly used by patients with type II diabetes. At present, it is the first-line hypoglycemic drug recommended by Chinese guidelines and foreign guidelines. The main pharmacological effect is to inhibit liver glucose output and improve peripheral tissues’ insulin resistance. Sensitivity to glucose, increase glucose uptake and standby, so as to reduce blood sugar, metformin can reduce glycosylated hemoglobin by 1%-2%. In addition, metformin does not increase weight and does not cause hypoglycemia when used alone. This is also a relatively large advantage of metformin in terms of safety. Studies in recent years have shown that metformin has other effects besides lowering blood sugar, such as improving blood lipids, lowering triglyceride and cholesterol levels, and also reducing platelet aggregation, so it is beneficial to delay or improve vascular complications in diabetic patients . Metformin also has the effect of suppressing appetite, and many obese patients are more suitable to use metformin for weight loss. In short, metformin is a relatively effective drug for lowering blood sugar.

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