2,4,5-Trifluorobenzylbromide

Name: 2,4,5-Trifluorobenzylbromide
Availability: 2-4-5-trifluorobenzylbromide-297582.html

Category:Intermediates
Product Name:2,4,5-Trifluorobenzylbromide
CAS No.:157911-56-3
Standard:USP
Price(USD):Negotiable
Company:Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

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Basic Info

Grade: pharmaceutical grade

Factory Location: china

Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa
Packaging Information: 1kg/bag
Sample Provided: no

Payment Terms: Bank transfer

2,4,5-Trifluorobenzyl bromide is an important intermediate in the synthesis of sitagliptin. Sitagliptin is the first dipeptidyl peptidase-IV (DPP-IV) inhibitor developed by Merck and approved by the US FDA in October 2006 for the treatment of non-insulin-dependent (type II) diabetes. 2,4,5-trifluorobenzyl bromide is prepared by bromomethylation of 1,2,4-trifluorobenzene as raw material, which has more waste and needs to use highly toxic cyanide, and the process has certain safety risks.

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