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The New Indication of Venetoclax, a Popular Drug of AbbVie, Declared in China
Dupeipei/PharmaSources
July 03, 2023
On June 21, Class 5.1 import application for 「Venetoclax tablet」 submitted by AbbVie was accepted by the CDE.
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NICE recommend venetoclax and azacytidine for patients with aggressive blood cancer
PharmaTimes
December 17, 2021
Venetoclax is an oral once-daily treatment, which blocks the action of the B-cell lymphoma-2 protein, the presence of which helps cancer cells survive.
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Imbruvica®-based regimens induce lasting remissions in leukaemia trials
europeanpharmaceuticalreview
May 21, 2021
Imbruvica® (ibrutinib) plus ventoclax and single-agent Imbruvica induced remissions lasting up to seven years in first-line treatment of chronic lymphocytic leukaemia.
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Actinium Completes Enrollment of Second Dose Cohort in Actimab-A Venetoclax Combination Trial
americanpharmaceuticalreview
April 02, 2021
Actinium Pharmaceuticals announced that initial patient enrollment in the second dose cohort in the Phase 1 portion of the Actimab-A venetoclax Phase 1/2 combination trial in fit and unfit patients with relapsed or refractory Acute Myeloid Leukemia ...
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Two medicines accepted for use by NHS Scotland
pharmatimes
December 09, 2020
The Scottish Medicines Consortium has approved NHS funding for treatments for blood cancer and a rare muscle disorder.
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NICE recommends new chemo-free chronic lymphocytic leukaemia treatment
europeanpharmaceuticalreview
November 16, 2020
More than 1,000 people each year could benefit from treatment with a combination of venetoclax and obinutuzumab, according to NICE.
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Positive results announced for acute myeloid leukaemia treatment trial
europeanpharmaceuticalreview
March 27, 2020
Positive topline results have been announced from a Phase II trial of VENCLEXTA® (venetoclax) in combination with azacitidine in patients with acute myeloid leukaemia (AML).
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VENCLEXTA, Low-Dose Cytarabine Combination Study for AML Does Not Meet Primary Endpoint
americanpharmaceuticalreview
March 04, 2020
AbbVie announced the VIALE-C (M16-043) trial of venetoclax (VENCLEXTA®) in combination with low-dose cytarabine (LDAC) versus LDAC in combination with placebo did not meet its primary endpoint of ...
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Curis Announces Positive Data in Ongoing Study of Fimepinostat, Venetoclax Combo
americanpharmaceuticalreview
December 12, 2019
Curis announced preliminary tolerability and PK data from its ongoing Phase 1 dose-finding study of fimepinostat, a small molecule dual inhibitor of PI3K/HDAC and suppressor of MYC ...
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Trovagene Announces Data Showing Ability of Onvansertib to Rescue Venetoclax-Resistance in AML
americanpharmaceuticalreview
December 11, 2019
Trovagene announced new in-vitro and in-vivo data suggesting that onvansertib may provide a new therapeutic option for patients who develop resistance to frontline treatment with venetoclax.