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Bristol Myers Squibb Receives European Commission Approval of Zeposia for Ulcerative Colitis
AmericanPharmaceuticalReview
December 01, 2021
Bristol Myers Squibb today announced that the European Commission has granted a Marketing Authorization for Zeposia (ozanimod) for the treatment of adults with moderately to severely active ulcerative colitis (UC) who have had an inadequate response...
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Six Proteins Upregulated Years Before Ulcerative Colitis Diagnosis
Drugs
November 25, 2021
Six inflammatory proteins are upregulated in plasma several years before diagnosis of ulcerative colitis, according to a report published in the November issue of Gastroenterology.
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Theravance Biopharma, Inc. Announces Top-line Results from Phase 2b Dose-Finding Induction Study of Izencitinib in Patients with Ulcerative Colitis
drugs
August 24, 2021
Theravance Biopharma, Inc. today announced top-line results from its Phase 2b dose-finding induction study of izencitinib, an orally administered, gut-selective pan-Janus kinase (JAK) inhibitor in development for the treatment of ulcerative colitis.
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Seres’ ulcerative colitis candidate misses primary endpoint in mid-stage study
pharmatimes
July 26, 2021
Microbiome therapeutics company Seres Therapeutics has announced that a Phase IIb study of its potential ulcerative colitis (UC) candidate SER-287 failed to meet its primary endpoint.
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Mirikizumab Up-Regulates Genes Associated with Mucosal Healing in Ulcerative Colitis for Up to One Year in Phase 2 Study
drugs
July 16, 2021
Eli Lilly and Company (NYSE: LLY) announced new Phase 2 data showing that gene expression changes induced by mirikizumab in patients with ulcerative colitis (UC) over a 12-week induction treatment were maintained for up to one year.
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Galapagos’ filgotinib leads to rapid symptom improvement for ulcerative colitis patients
pharmatimes
July 13, 2021
A post-hoc analysis from a Phase III clinical programme evaluating Galapagos’ filgotinib showed significant symptom improvements for patients with ulcerative colitis (UC).
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Rinvoq scores positive results as a maintenance therapy for ulcerative colitis
pharmatimes
July 02, 2021
AbbVie’s JAK inhibitor Rinvoq met the primary and all secondary endpoints in a Phase III ulcerative colitis maintenance study, the company announced earlier this week.
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Bridge Biotherapeutics Announces the Initiation of Patient Dosing in the Proof of Clinical Principle Study for BBT-401, an Investigational Drug for Ulcerative Colitis
prnasia
June 15, 2021
Bridge Biotherapeutics (KQ288330) announced the first patient dosing of BBT-401 at mid to high doses in its proof of clinical principle (PoCP) study to examine the drug's efficacy and safety in active ulcerative colitis (NCT04596293).
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Bridge Biotherapeutics Announces the Initiation of the Proof of Mechanism Study for BBT-401 in Patients with Ulcerative Colitis; Rectal Delivery of Drug to Target Site
prnasia
June 02, 2021
Bridge Biotherapeutics today announced the first patient dosing of BBT-401 in its open label, proof of mechanism study to examine the drug's efficacy and safety in active ulcerative colitis when delivered rectally to the colon (NCT04478825).
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U.S. FDA Approves an Oral Treatment for Adults with Ulcerative Colitis
americanpharmaceuticalreview
June 02, 2021
Bristol Myers Squibb announced that the U.S. FDA approved Zeposia® (ozanimod) 0.92 mg for the treatment of adults with moderately to severely active ulcerative colitis (UC), a chronic inflammatory bowel disease (IBD).