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Research showed that treatment with the androgen-blocking drug enzalutamide reduced TMPRSS2 levels in lab cultures of human lung cells. It significantly reduced SARS-CoV-2 entry and infection in lung cells.
Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the ...