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Powder Flow: Limitations of Mathematically Derived Parameters from Shear Cell Testing
Tim Freeman
August 03, 2020
Shear Cell testing was originally designed to determine the incipient flow of continuous, cohesive powders under applied stress in order to simulate flow from a hopper/silo.
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Powder Flow: Optimising Unit Operations using the FT4 Powder Rheometer®
Tim Freeman
June 24, 2020
Powder Flow: Manufacturing Support using the FT4 Powder Rheometer®
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WEBINAR: POWDER FLOW ENHANCEMENT IN BATCH AND CONTINUOUS PROCESSES
Tim Freeman
June 17, 2020
Poor flow can lead to processing problems, e.g. inconsistent feeding, air entrainment, but more importantly also to rejections due to compromised dosage uniformity. Active Pharmaceutical Ingredients (APIs) in particular often exhibit poor flowability.
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Powder Flow: Manufacturing Support using the FT4 Powder Rheometer®
Tim Freeman
May 24, 2020
By investing in powder rheology, manufacturing sites can establish an understanding of their processes and unit operations based on a correlation between measurable powder properties and process performance.
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Powder Flow: Influence of Powder Properties on Dosing Performance
Tim Freeman
March 25, 2020
Dry Powder Inhalers (DPI) are used to deliver a controlled dose of active pharmaceutical ingredient (API) to the deep lung.
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Powder Flow: A QbD approach to Continuous Tablet Manufacture
Tim Freeman
January 16, 2020
Utilising the FT4 Powder Rheometer® and the GEA ConsiGmaTM Twin Screw High Shear Granulator
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Powder Flow: Characterising Wet Masses using the FT4 Powder Rheometer
Tim Freeman
December 13, 2019
The presence of free water can fundamentally influence the flow properties of a powder.
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Powder Flow: The Influence of Flow Additives on Powder Behaviour
Tim Freeman
November 14, 2019
Many powders have poor basic flow properties: They block in hoppers and die feed frames, exhibit inconsistent or pulsatile discharge rates, adhere to surfaces of equipment or don’t mix readily with other materials.
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Powder Flow: Using Powder Rheology to Develop Generic Dry Powder Inhaler Formulations
En-CPhI
October 17, 2019
Dry Powder Inhalers (DPIs) are used to deliver a controlled dose of active pharmaceutical ingredient (API) to the deep lung.
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Powder Flow:The importance of a sachet filling process with low weight variation and high content uniformity
Tim Freeman
September 25, 2019
It is imperative that the sachet filling process produces consistent, uniform fill throughout an entire production run, with low weight variation and high content uniformity.