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The Classification of Sesquiterpene Compounds and Their Research Progress
Xiaomichong
May 23, 2024
Terpenoids are an important part of natural organic compounds, and there are currently more than 50,000 reported terpenoid structures.
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Spray Drying: Addressing poor solubility and Bioavailability of drugs (Part II)
Deepak Hegde
December 27, 2023
This article, which is Part 2 of the series on address some of the practical considerations in application of spray drying to later phases of development.
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R&D Status of Drugs Based on Influenza Pathogenesis (Part Two)
PharmaSources/Xiao Michong
March 16, 2022
Influenza virus RNA polymerase is a protein complex composed of PA, PB1 and PB2 subunits. PA has endonuclease activity and can induce proteolysis. PB1 has RNA polymerase activity...
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Novel antibody helps block COVID transmission in cells, finds study
ExpressPharma
February 15, 2022
The antibody, FuG1, targets the enzyme furin, which the virus uses for its efficient chain of infections in human cells.
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Novartis seeks FDA EUA for Covid-19 antiviral candidate ensovibep
Pharmaceutical-Technology
February 14, 2022
Molecular Partners has reported that its partner Novartis sought emergency use authorization (EUA) for the antiviral candidate, ensovibep, from the US Food and Drug Administration (FDA) to treat Covid-19.
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Plant “biofactories” produce proteins for potential COVID-19 vaccine
EuropeanPharmaceuticalReview
February 10, 2022
COVID-19 is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). SARS-CoV-2 replicates by infecting human cells via the interaction of the receptor-binding domain (RBD) on the viral Spike (S) protein...
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Suppressing the spread of tumors
WorldPharmaNews
February 09, 2022
Why some patients develop metastases and others do not is largely unclear. Researchers around ISTA professor Daria Siekhaus are now contributing to a better understanding of the process in certain types of cancer.
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Amgen and Plexium announce multi-year, drug discovery collaboration to identify novel targeted protein degradation therapies
WorldPharmaNews
February 07, 2022
Amgen (NASDAQ:AMGN) and Plexium, Inc. (Plexium) today announced an exclusive, worldwide, multi-year research collaboration and license agreement to identify novel targeted protein degradation therapeutics...
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Lonza Drug Product Services Participates in RealHOPE Project
contractpharma
January 19, 2022
Initiative aims to measure real-life events during drug handling that can destabilize protein-based therapeutics.
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Frontier Medicines Advances First Target Under Abbvie Alliance
contractpharma
January 10, 2022
Continues to advance its ongoing efforts and strategic focus on difficult-to-drug protein targets.