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Closing the door: breaking new ground related to a potential anticancer drug target worldpharmanews
August 02, 2019
In order to sustain fast growth, cancer cells need to take up nutrients at a faster rate than healthy cells. The human glutamine transporter ASCT2 allows the amino acid glutamine to enter cells and is upregulated in many types of cancer cells ...
Modified vaccinia virus shows potential in fighting sarcoma tumours pharmatimes
June 18, 2019
New research published in the Clinical Cancer Research has found that modified versions of the vaccinia virus have boosted immunotherapy in sarcoma tumours; a hard-to-treat cancer.
Novartis CEO touts 25 potential—and diverse—blockbuster launches. But is its portfolio too scattered? fiercepharma
May 29, 2019
Just over a year into his reign as Novartis CEO, Vas Narasimhan proudly spotlighted 25 potential blockbuster launches coming down the pipeline. But that figure also begs the question: Is the company dabbling in too many different therapeutic areas and pla
Japanese scientists reveal potential of technology to detect cancer biospectrumasia
April 29, 2019
The scientists present a technique that makes use of the binding properties of aptamers, synthetic organic molecules acting as probes for cancer cells.
First RXC006 data suggests it has great potential for the treatment of fibrosis firstwordpharma
December 02, 2018
In the first public disclosure of data on RXC006, Dr Peter Bunyard, Head of Fibrosis at Redx, presented results from preclinical studies in a plenary session as well as a poster which showed that RXC006 was highly effective at suppressing the Wnt pathway
Mouse study reveals potential new treatment for inherited deafness fiercebiotech
July 09, 2018
A decade ago, NIH researchers studying an inherited type of deafness in a single extended family managed to identify the mutation responsible. They named the family's condition DFNA27 deafness, after the region on chromosome 4 where the mutation resides.
New ‘genetic atlas’ of plasma proteins could unveil potential drug targets fiercebiotech
June 11, 2018
Identifying genetic variants that control disease-causing blood proteins isn’t an easy task. A team led by scientists at the University of Cambridge and Merck & Co. has created a “genetic atlas” of such genetic links that could help reveal biomarkers for
FDA to Review Zynquista (sotagliflozin) as Potential Treatment for Type 1 Diabetes drugs
May 31, 2018
The U.S. Food and Drug Administration (FDA) has accepted Sanofi's regulatory filing for Zynquista (sotagliflozin). The investigational oral treatment would be used in addition to insulin therapy to improve blood sugar control in adults with type 1 diabete
Birth Control Pills (Taytulla Physician Sample Packs) Recalled Over Potential Pregnancy Risk drugs
May 31, 2018
Almost 170,000 birth control pill packs are being recalled over a manufacturing error that could lead to unplanned pregnancy, maker Allergan says.