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Monday, the drugmakers reported that their immuno-oncology drug had failed a phase 3 trial in previously treated ovarian cancer patients, failing to stave off cancer progression or prolong life either on its own or in tandem with chemo.
Merck KGaA and Pfizer’s late entrant to the checkpoint inhibitor category has failed a phase III trial in ovarian cancer, denting their hopes of building momentum for the product.
Merck KGaA and Pfizer’s Bavencio (avelumab) has missed its primary endpoints in the treatment of platinum-resistant or -refractory ovarian cancer, whether as a monotherapy or in combination with chemotherapy.