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Burden of Rare Genetic Variants Higher in Severe Schizophrenia Drugs
December 14, 2021
Individuals with severe, extremely treatment-resistant schizophrenia have an increased burden of high-impact rare genetic variants, according to a study published in the Dec. 21 issue...
Scientists Uncover More Autism Genes drugs
August 14, 2019
In a finding that underscores the major role genetics plays in autism risk, researchers report they have identified 16 new genes linked to the developmental disorder.
Neratinib defeats the Ras genes notorious for causing cancer europeanpharmaceuticalreview
May 06, 2019
Breast cancer drug neratinib has been found to block the function of the Ras genes which are among the first to be linked to cancer development…
When a cell's 'fingerprint' can be a weapon against cancer worldpharmanews
March 14, 2019
The study published in the scientific journal PLoS Computational Biology shows the types of tumors in which these genes are most active and identifies drugs with the potential to selectively eliminate cells that carry that label.
Genetic study reveals possible new routes to treating osteoarthritis worldpharmanews
January 23, 2019
In the largest genetic study of osteoarthritis have uncovered 52 new genetic changes linked to the disease, which doubles the number of genetic regions associated with the disabling condition.
Research on Almost 2,000 Brains Brings Insight Into Mental Illness drugs
December 14, 2018
Researchers say a massive genetic analysis of the human brain has yielded new insights into the underpinnings of psychiatric diseases such as schizophrenia, bipolar disorder and autism......
Largest census of cancer genes to help understand drug targets worldpharmanews
October 25, 2018
Researchers at the Wellcome Sanger Institute have created the first comprehensive summary of all genes known to be involved in human cancer, the "Cancer Gene Census".
UK researchers find 40 genes associated with myeloma pharmaceutical-technology
April 11, 2018
Researchers at the Institute of Cancer Research in the UK have discovered 40 genes involved in the development of myeloma, a form of blood cancer.
Four genes linked to pancreatic cancer identified biospectrumasia
November 07, 2017
The team found that patients who had three or four of the altered genes had worse disease-free survival - the time between surgery and when the cancer returns - and overall survival - from surgery to death - compared to patients with a single or two alter
New study discovers faulty genes underlying brain tumours pharmaceutical-technology
July 31, 2017
A new in-depth study funded by Cancer Research UK has shown that medulloblastoma brain tumours have faulty genes underlying the disease.