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Novartis terminates remestemcel-L development agreement with Mesoblast
Pharmaceutical-Technology
December 16, 2021
Novartis has cancelled an agreement to develop, produce and market Mesoblast’s mesenchymal stromal cell (MSC) product remestemcel-L.
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Stem cell therapy shows promise in COVID-19 respiratory distress
europeanpharmaceuticalreview
May 26, 2021
JadiCell™ was shown to significantly improve survival in COVID-19 patients with Acute Respiratory Distress Syndrome (ARDS) and also reduce lung scarring associated with long-COVID-19.
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Sorrento gets Brazilian ANVISA’s clearance for Phase II Covid-19 trial
pharmaceutical-technology
May 24, 2021
Sorrento Therapeutics has received clearance from the Brazilian regulatory agency ANVISA to conduct a Phase II clinical trial of an injectable infusion of mesenchymal stem cells, COVI-MSC, to treat Covid-19 patients with acute respiratory distress ...
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Veru initiates enrolment in Phase III trial of sabizabulin for Covid-19
pharmaceutical-technology
May 20, 2021
Veru has enrolled the first subject in Phase III clinical trial of sabizabulin to treat hospitalised Covid-19 patients who are at high risk for acute respiratory distress syndrome (ARDS).
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Mesoblast’s remestemcel-L lowers mortality in Covid-19 ARDS patients
pharmaceutical-technology
May 06, 2021
Mesoblast has reported that results from a trial showed remestemcel-L reduced mortality in ventilator-dependent Covid-19 patients aged below 65 years with moderate/severe acute respiratory distress syndrome (ARDS) through day 60 by 46%.
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Foresee Pharmaceuticals Announces Dosing of First Patient in Phase 2/3 Clinical Trial of FP-025 for Treatment of COVID-19 Associated ARDS
prnasia
March 29, 2021
Foresee Pharmaceuticals Co., Ltd., today announced the initiation of patient dosing in the Phase 2/3 clinical trial of FP-025, its highly selective oral MMP-12 inhibitor, in adult patients with severe to critical COVID-19 with ...
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Longeveron Expands Enrollment Criteria for Trial Evaluating Lomecel-B Infusion ARDS due to COVID-19
americanpharmaceuticalreview
March 11, 2021
Longeveron announced enrollment criteria for its Phase 1 Acute Respiratory Distress Syndrome (ARDS) RECOVER trial has been expanded to include mild ARDS, in addition to moderate and severe ARDS. Previously, only ARDS patients intubated with ...
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Cerecor’s antibody reduces respiratory failure in Covid-19 ARDS trial
pharmaceutical-technology
March 03, 2021
Cerecor has reported that final efficacy data from Phase II trial of human anti-LIGHT (TNFSF14) monoclonal antibody, CERC-002, in hospitalised patients with Covid-19 linked pneumonia and mild-to-moderate acute respiratory distress syndrome (ARDS) met ...
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Veru reports positive data from Phase II Covid-19 drug trial
pharmaceutical-technology
February 10, 2021
Veru has reported positive efficacy and safety results from Phase II clinical trial of an oral drug, VERU-111, in hospitalised Covid-19 patients at high risk for Acute Respiratory Distress Syndrome (ARDS).
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Desidustat prevents development of ARDS in Phase II COVID-19 trial
europeanpharmaceuticalreview
January 28, 2021
In a Phase IIb trial, hospitalised COVID-19 patients treated with desidustat did not develop acute respiratory distress syndrome (ARDS).