Antibiotics Have Characteristics Different from Chemical Drugs

Ⅰ. Know about antibiotics

Antibiotics are secondary metabolites of microorganisms, neither involved in cell structure nor intracellular storage nutrients, and are harmless to the producing bacteria themselves. However, it has an antagonistic effect on some microorganisms, which is a defense mechanism for microorganisms to defeat other microorganisms in interspecies competition to protect themselves. The bacteriostatic or bactericidal effect of antibacterial agents such as antibiotics is mainly aimed at killing the mechanism that "bacteria have, but humans (or other animals and plants) do not", including four major mechanisms of action. Namely: inhibit bacterial cell wall synthesis, enhance bacterial cell membrane permeability, interfere with bacterial protein synthesis and inhibit bacterial nucleic acid replication and transcription.

Ⅱ. Antibiotics have different characteristics from chemical drugs:

1. Antibiotics can selectively act on specific links in the DNA, RNA and protein synthesis systems of human cells, interfere with the metabolism of cells, hinder life activities or stop growth, or even die. Unlike ordinary disinfectants or fungicides that are not selective. The antibacterial activity of antibiotics is mainly manifested in three phenomena: bacteriostatic, bactericidal and bacteriostatic. There are no sharp boundaries between these three roles. The antibacterial effect of antibiotics is related to the concentration of use, the duration of action, the species of sensitive microorganisms and the surrounding environmental conditions. If you are looking for different kinds of antibiotics and antibiotics suppliers, Pharmasources would be a great platform for you.

2. The effect of antibiotics is selective, and different antibiotics have different effects on different pathogens. The species of pathogenic bacteria that are susceptible to an antibiotic is called the antibiotic spectrum (antibacterial spectrum). For example, intellectin produced by Streptomyces lilacinus has only a medical effect on a few viruses, and has no effect on bacteria, fungi and most other viruses. Broad-spectrum antibiotics have antibacterial effects on a variety of pathogenic bacteria. For example, penicillin has a good effect on a variety of Gram-positive bacteria, streptomycin has a good effect on a variety of Gram-positive and negative bacteria, and has a special effect on Mycobacterium tuberculosis.

3. Effective concentration. Antibiotics are a physiologically active substance. All kinds of antibiotics generally act on pathogenic bacteria at very low concentrations, which is another main feature that distinguishes antibiotics from other chemical fungicides. The effective concentrations of various antibiotics to different microorganisms are different. Usually, the lowest concentration that inhibits the growth of microorganisms is used as the antibacterial strength of the antibiotic, which is referred to as the effective concentration. The lower the effective concentration, the stronger the antibacterial effect. Antibiotics with an effective concentration above 100 mg/L are antibiotics with low action intensity, and those with an effective concentration below 1 mg/L are antibiotics with high action intensity.