Precautions for Taking Sulfonamides Drugs

Sulfonamide drugs still occupy a certain position in the anti-infective drugs because they have good curative effect on some infectious diseases, and have the advantages of convenient use, stable nature and low price. But there are a few things to keep in mind when taking sulfa drugs.

1. Use of sulfonamide drugs to master the indications

The main indications of sulfonamide drugs are meningitis, bacillary dysentery, enteritis, plague and various infections caused by hemolytic streptococcus, pneumococcus, staphylococcus aureus, Escherichia coli, proteus, etc. It can prevent meningitis and rheumatism hot. But it is not effective for viral diseases such as angina, sore throat and upper respiratory tract infection. Sulfonamide drugs should not be taken for unexplained fever to avoid delay in diagnosis and treatment. At the same time, after using sulfonamide drugs for a period of time, drug resistance will develop. Once drug resistance occurs, all sulfonamide drugs will fail. At this time, other antibacterial drugs should be quickly replaced.

2. Pay attention to the dosage of sulfonamide drugs

The first dose of sulfonamide drugs should be doubled to achieve rapid bacteriostasis, and then the maintenance dose (ie, normal dose) should be used. After the symptoms disappear, the last dose should be given 2 to 3 times (the minimum dose). In order to maintain the efficacy of the drug for a long time and prevent the bacteria from rebounding; during the medication, remember not to arbitrarily increase the dosage, increase the frequency of medication or prolong the course of treatment to prevent drug accumulation and poisoning. If you are looking for different types of sulfonamides drugs, Pharmasources would be a great platform for you.

Sulfonamide drugs can easily cause neutropenia, thrombocytopenia and aplastic anemia. During the treatment period, the changes of peripheral blood should be checked regularly; liver damage can cause jaundice, liver dysfunction, and liver necrosis in severe cases. Patients with liver disease should avoid the use of this type of drugs; renal damage, renal function should be monitored during medication, renal dysfunction, dehydration, shock and elderly patients are prone to aggravate or develop renal damage, and should be avoided. Because sulfonamide drugs can cause dizziness, headache, fatigue, malaise and insomnia and other mental symptoms in a small number of patients, they should not engage in high-altitude work and driving during the medication period.

3. The details of using sulfonamide drugs should not be ignored

Some sulfonamide drugs have very little solubility in urine. In order to increase their solubility, baking soda tablets should be taken at the same time to make the urine alkaline; secondly, the patient should be instructed to drink more water and increase the amount of urine to reduce the concentration of the drug in the urine. Nausea, vomiting, loss of appetite and stomach pain often occur when taking it on an empty stomach. It can be relieved by swallowing it after meals or with rice soup. Those who are allergic to sulfonamide drugs and patients with megaloblastic anemia should not use it. Pregnant and breastfeeding women should avoid use. Babies less than two months old are also absolutely prohibited. Elderly patients should avoid using it. If there is an indication, it should be applied after weighing the pros and cons.