PharmaSourcesJuly 13, 2021
Tag: Budesonide , API Powder , corticosteroid
Budesonide is a corticosteroid with anti-inflammatory and immunomodulating effects. It is used to treat several respiratory and digestive conditions. Common brand names include Entocort, Pulmicort, and Rhinocort Aqua.
Budesonide is available in an API powder, inhaler, inhalation suspension, nasal spray, and capsule.
Budesonide API powder (CAS 51333-22-3) is in the form of a white or almost white crystalline powder. The minimum specification from Chinese manufacturers Aurisco Pharmaceutical Co., Ltd., Shandong Taihua Biotech. Corporation Ltd., Amphaster Nanjin Pharmaceuticals Inc, Hunan Yuxin Pharmaceutical Co., Ltd., and HuNan Kerey Pharmaceutical Co., Ltd. is 99%.
Budesonide is available as an inhaler under the brand name Pulmicort. It is supplied as a 90 mcg or 180 mcg flexhaler.
Budesonide is available as an inhalation suspension in generic and the brand name, Pulmicort or Pulmicort Respules. The inhalation suspensions are supplied in 0.25 mg/2 mL, 0.5 mg/2 mL, and 1 mg/ 2 mL ampules.
Budesonide is available as a nasal spray in generic and brand name, Rhinocort Aqua. The nasal sprays are supplied in 8.6 g of 32 mcg concentrations.
Budesonide is available in a 3 mg strength capsule in generic and the brand name, Entocort.
Budesonide is an inhaled corticosteroid used to control respiratory conditions. In contrast, albuterol is a short-acting bronchodilator used for rescue or quick relief of respiratory conditions.
Short term, corticosteroids exert their mechanism of acting by causing decreased vasodilation, capillary permeability, and decreased leukocytes at inflammation sites (PubChem). In addition, corticosteroids bind to the glucocorticoid receptor, interfering with gene expression that causes various downstream effects over hours or even days (PubChem). Glucocorticoids impede the death of neutrophils and demargination; they inhibit phospholipase A2, reducing the production of arachidonic acid derivatives; they inhibit other inflammatory transcription factors yet promote anti-inflammatory genes (PubChem).
Budesonide is manufactured in accordance with good manufacturing practices to ensure the safest and highest quality API. According to PubChem, budesonide API is manufactured by the conversion of 11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione to the 16,17-acetal with butyraldehyde.
Budesonide is used to treat many respiratory conditions including allergies, asthma, COPD, and hay fever. It is also used to treat digestive conditions such as Crohn’s disease.
Common side effects of budesonide include easy bruising, chills, cough, diarrhea, general discomfort, headache, hoarseness, joint pain, loss of appetite, muscle aches, nausea, sore throat, sweating, trouble sleeping, and tiredness.
According to MarketWatch, the global budesonide market size was USD 8073 million in 2020 and is predicted to grow at a CAGR of 3.2% and reach USD 9909.5 million by 2027.
Below are some Chinese manufacturers who are professional in making API pharmaceutical ingredient.
Aurisco Pharmaceutical Co., Ltd., Shandong Taihua Biotech. Corporation Ltd., Amphaster Nanjin Pharmaceuticals Inc, Hunan Yuxin Pharmaceutical Co., Ltd., and HuNan Kerey Pharmaceutical Co., Ltd. manufacture bulk 99% budesonide API powder. If you need a price quote, certificate of analysis (COA), or a detailed specification sheet, please visit these budesonide API suppliers on www.pharmasources.com.
Established in 2002, Aurisco Pharmaceutcal Co., Ltd. uses innovation to develop and manufacture pharmaceuticals to companies worldwide. They are broadening their scientific and technology scopes while ensuring environmentally safe and high-quality products. Their creativity and dedication are important for their future growth and success.
To learn more about Aurisco Pharmaceutical Co., Ltd. and the services they provide, please visit pharmasources.com.
Established in 2004, Shandong Taihua Biotech. Corporation Ltd. is now a leader in the manufacturing of raw materials of steroids. They are professional and skilled, abiding by the requirements of good manufacturing practices to ensure safe and high-quality products.
For more information about Shandong Taihua Biotech. Corporation Ltd. and their services, please visit pharmasources.com.
Amphaster Nanjin Pharmaceuticals Inc was established in 2009. They are now a technologically advanced company of research, development, manufacturing, and sales of thrombolytic, asthma, Alzheimer’s disease, and other conditions.
To learn more about the services offered by Amphaster Nanjin Pharmaceuticals Inc, please visit pharmasources.com.
Hunan Yuxin Pharmaceutical Co., Ltd. was established in 2002. They follow good manufacturing practices as they manufacture steroid and hormone pharmaceutical APIs and intermediates for global pharmaceutical companies. They are dedicated to customer satisfaction and welcome cooperation with customers and businesses around the world.
For more information about Hunan Yucin Pharmaceutical Co., Ltd. and their services, please visit pharmasources.com.
Founded in 2001, HuNan Kerey Pharmaceutical Co., Ltd. specializes in the manufacturing and sales of pharmaceutical intermediates for companies domestic and global. They use the latest equipment to ensure high quality product. They believe that the concept “Quality & Integrity the Priority” will help contribute to a better future for the world.
Learn more about HuNan Kerey Pharmaceutical Co., Ltd. and their services on pharmasources.com.
Visit PharmaSources.com to find the highest quality manufacturers, exporters, suppliers, and buyers of API and intermediates. PharmaSources is a platform that has expanded their services to more than 900,000 active members across 211 countries and regions. They display over 1,600,000 products in 30 major categories, making their mission “to connect global buyers with quality suppliers and facilitate easy trade of the pharmaceutical industry” (PharmaSources).
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