americanpharmaceuticalreviewOctober 10, 2020
Tag: AVACEN , Type 2 diabetics , PBG
AVACEN Medical announced the completion and results from the second part of its sponsored 50 person study of glucose tolerance in Type 2 diabetics.
The double-blind randomized controlled pilot study with crossover design focused on postprandial blood glucose (PBG) reduction consequential to use of the AVACEN 100 dry heat therapy medical device. The AVACEN device is believed to have the ability to overcome disease-induced microvascular impairment by mechanically recruiting the microvasculature allowing for glucose disposal. PBG is an independent predictor of all-cause mortality, cardiovascular disease and cardiac events.
Furthermore, recent 3rd party research has revealed that diabetes is associated with greater pulmonary inflammation and that successful blood glucose management is effective in fighting serious cases of COVID-19.
The IRB approved study was conducted in the Clinical Nutrition and Physiological Sciences Laboratory in conjunction with The School of Exercise and Nutritional Sciences at San Diego State University. Michael J. Buono, Ph.D., Professor School of Exercise and Nutritional Sciences and the Department of Biology acted as Principal Investigator.
"The SDSU study demonstrates that the AVACEN negative pressure heat treatment may overcome microvascular damage caused by Type 2 diabetes. They also show significant reductions in lowering post prandial blood glucose compared to non-treated controls. I look forward to further evaluation of this device in larger series of patients, both Type 2 diabetics as well as long standing insulin dependent Type 1 diabetic patients," Jonathan RT Lakey, PhD, MSM, professor of surgery and biomedical engineering at UC Irvine aid.
Type 2 diabetes currently constitutes a global crisis. It stands as a leading cause of both death and disability in countries of all income levels, directly costing nearly a trillion dollars to the world.
While largely considered a preventable and reversible disease, Type 2 diabetics continues to increase in prevalence in individuals of all ages. Even though exercise and diet are effective in lowering blood glucose, adherence is often poor. Globally, one in three women and one in four men do not meet the physical activity guidelines.
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