PharmaSources/Keith J. MyersOctober 20, 2020
Tag: C B D Oil , C B D Oil Side Effects , Cannabidiol
Cannabidiol (C B D) has gained immense popularity for its ability to deal with various health conditions such as anxiety, insomnia, and chronic pain.
Though C B D has been found to be very helpful in treating various medical conditions, one of the biggest concerns that we have is its side effects and how it interacts with other drugs. There are many researches going on to prove the safety and effectiveness of the drug. According to the research to date, C B D is safe and has some minor side effects. However, there are certain considerations when it comes to interactions with drugs. Thus, it is imperative that one should know how the body metabolizes some substances in this regard. In this article, we are going to discuss the C B D drug interactions and its side effects that ever C B D user should know.
How C B D interacts with medication and drugs:
C B D inhibits the activity of cytochrome P450 and it also increases or decreases the impact of certain medicines by interacting with the ECS (Endocannabinoid System). Following are the ways in which C B D interacts with various compounds:
Interaction of C B D with blood-thinning drugs- Increased risk of bleeding
According to studies, C B D can increase the effects of those drugs that are used for blood thinning. There are some drugs that are used for blood thinning while other drugs are those that cause blood thinning as a side effect. If you consume these drugs along with C B D oil, interaction can occur.
C B D slows down the metabolism of these drugs by the body and increases the duration of these drugs in the body. In short, C B D can increase the effect of those drugs that cause blood thinning, and thus increase the risk of bleeding.
Interaction of C B D with anti-seizure medicines- occurrence of aggressive seizures
C B D is used as an effective treatment for seizures, but without proper medical supervision, it can cause issues by interacting with anti-seizure medicines. When C B D is used in low quantities, it doesn’t produce anti-epileptic effects, instead, it keeps on inhibiting the cytochrome P450 enzymes and prolongs the concentration of or clobazam and clobazam in the body. The concentration of these compounds increases seizures and makes them more aggressive. Thus, the proper dosage of C B D must be taken to avoid this issue.
Interaction of C B D with sedatives- causes the additive effect
When C B D interacts with sedatives, it affects the neuro-receptors that are present in the central nervous system. The C B D thus produces an additive effect and prolongs the effect of this medicine. The interaction of C B D with the sedatives don’t cause any direct harmful effect, but the overall effect can be different from what the sedatives are given for. To make sure you’re safe from this interaction, you should avoid having C B D and the sedatives simultaneously.
Interaction of C B D with chemotherapy drugs- Inhibition of metabolism
Chemotherapy is used for the treatment of cancer and thus accurate quantities of the drugs play a very important role here. The chemotherapy drugs are created in a way that they are metabolized before entering the body, however, if C B D is introduced to the body at the same time, this process is inhibited. The C B D thus causes chemotherapy drugs to increase in concentration in the bloodstream. This way the drugs’ presence in the body is prolonged and they can cause more harm than benefit.
Side effects to watch for:
With proper medical supervision, you can safely use C B D along with the drugs and medications. It is, however, recommended that you watch out for any changes that might occur due to the interaction of C B D and the drugs. Following are the side effects to watch for:
A decrease in the effectiveness of medication which can cause sudden seizures.
Any prolonged side effects or problems due to medicines that you newly started, such as drowsiness, sedation, and nausea.
Some of the common side effects caused by C B D such as fatigue, diarrhea, appetite changes, and weight loss or gain.
Final thoughts:
It is always recommended to consult your doctor or medical advisor if you’re going to try C B D, especially if you’re taking certain medications or are suffering from a health condition. Your doctor will recommend the quality and dosage of C B D that will be safe for you and will suit your requirements.
References:
1、Possible Side Effects Of C B D Oil & Drug Interaction https://www.healthcanal.com/health/side-effects-C B D
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