americanpharmaceuticalreviewMarch 13, 2020
Tag: Tiziana , TZLS-501 , coronavirus
Tiziana Life Sciences has announced that its TZLS-501 treatment could be a potential treatment for patients infected with coronavirus (COVID-19) who are at risk of respiratory failure.
Tiziana, a biotechnology company focused on innovative therapeutics for inflammatory and autoimmune diseases, is expediting development of TZLS-501, with Novimmune, SA, a Swiss biotechnology company with whom it entered into a world-wide license for composition-of-matter in 2017.
Tiziana plans to administer TZLS-501 using a proprietary formulation technology. Tests have already shown that the treatment rapidly depletes circulating levels of IL-6 in the blood. An excessive production of IL-6 is regarded as a key driver of chronic inflammation and is believed to be associated with severe lung damage observed with COVID-19 infections and acute respiratory illness.
"We are excited to move forward with our clinical development plan to expedite evaluation in patients as soon as possible," Dr. Kunwar Shailubhai, CEO & CSO of Tiziana Life Sciences said.
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