Interventions More Likely After RYGB Versus Sleeve Gastrectomy

Among adults undergoing bariatric surgery, interventions, operations, and hospitalizations are more likely after Roux en Y gastric bypass (RYGB) than after sleeve gastrectomy (SG), according to a study published online Jan. 15 in JAMA Surgery.

Anita Courcoulas, M.D., from the University of Pittsburgh, and colleagues conducted a national, multicenter study of individuals undergoing RYGB and SG to compare the risks for intervention, operation, endoscopy, hospitalization, and mortality up to five years; the primary outcome was time until operation or intervention (OorI). Data were included for adults who underwent RYGB (18,056 adults) or SG (15,504 adults) at 10 centers in four clinical data research networks.

The researchers found that OorI was less likely for patients undergoing SG than RYGB (hazard ratio, 0.72), with estimated adjusted cumulative incidences of 8.9 and 12.3 percent, respectively, at five years. Hospitalization was less likely for SG than RYGB (hazard ratio, 0.82), with five-year cumulative incidences of 33 and 38 percent, respectively. Endoscopy was also less likely for SG (hazard ratio, 0.47), with adjusted cumulative incidences of 7.8 and 15.8 percent, respectively, at five years. All-cause mortality did not differ between the groups.

"What we advocate is high-quality shared decision making between providers and patients," Courcoulas said in a statement. "Some people value low risk, some value high weight loss. It's important to have information on both sides of the risk-benefit equation."

Register as Visitor to CPhI China 2020!

-----------------------------------------------------------------------
Editor's Note:

En-CPhI.CN is a vertical B2B online trade platform serving the pharmaceutical industry,

for any copyright disputes involved in the articles,

please email: Julia.Zhang@imsinoexpo.com to motify or remove the content.