WPD New Discovery for Cancer Targeting Drugs Granted Patent

WPD Pharmaceuticals announced Wake Forest University received a patent from the United States Patent and Trademark Office (USPTO) for patent 105019210 (issued under application number 16/262,195v) licensed to WPD. The patent is in respect to a protein critical in the development of Th2 immune responses, which are associated with allergy, asthma, fibrosis and aggressive forms of cancer.

IL-13 proteins were shown to be important factors in eliminating tumor cells related to various forms of cancer. Recombinant IL-13 protein armed with potent bacteria toxins preferentially bind to tumor-specific receptors and selectively deliver highly cytotoxic payload to tumor cells. This highly specific targeting of aggressive brain tumor glioblastoma (GBM) and other tumor cells is designed to allow for selective elimination of tumor cells by bacteria-toxins-induced cytotoxic effects without affecting normal cells. IL-13 protein can also assist in the survival and the development of tumor-associated immune cells, which could be beneficial for individuals with autoimmune diseases and forms of cancer associated with Th2 immune responses.

"WPD continues to develop its robust drug portfolio and the patent granted for our cancer targeting IL-13 proteins strongly protects our IP as we advance development of our brain cancer focused therapeutic program. We will continue to work closely with Wake Forest University on the IL-13 and Ephrine technology platforms to rapidly advance our current pre-clinical studies," Mariusz Olejniczak, CEO of WPD said.

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