FDA: Patients Should Not Abruptly Stop Taking a Prescribed Opioid

WEDNESDAY, April 10, 2019 -- Because of the danger of "serious harm" to patients, the U.S. Food and Drug Administration is advising doctors not to suddenly stop patients from taking opioid painkillers, or drastically lower the dose.

In a statement released Tuesday, the agency said it is adding a warning about sudden discontinuation of use to the prescribing information of opioid painkillers such as OxyContin (oxycodone), Vicodin (hydrocodone), morphine, and other drugs.

"Rapid discontinuation can result in uncontrolled pain or withdrawal symptoms," the agency explained. "In turn, these symptoms can lead patients to seek other sources of opioid pain medicines, which may be confused with drug seeking for abuse. Patients may attempt to treat their pain or withdrawal symptoms with illicit opioids, such as heroin, and other substances."

The new guideline is meant to help doctors allow patients who no longer require an opioid to safely wean themselves off the drug -- cutting their risk for withdrawal symptoms. Instead of cutting a patient off from their prescription opioid, physicians should "create a patient-specific plan to gradually taper the dose of the opioid and ensure ongoing monitoring and support, as needed, to avoid serious withdrawal symptoms, worsening of the patient's pain, or psychological distress," the agency advised.

Register as Visitor to CPhI China 2019!

-----------------------------------------------------------------------
Editor's Note:

To apply for becoming a contributor of En-CPhI.cn,

welcome to send your CV and sample works to us,

Email: Julia.Zhang@ubmsinoexpo.com.