PharmaSources.comDecember 06, 2017
Tag: Andrographis Extract , Andrographis Paniculata
What is Andrographis Extract?
Andrographis (Paniculata) extract, originates from herb Andrographis Paniculata, an annual herbaceous plant in the family Acanthaceae. Powder andrographis extract is prepared from aerial part of herb andrographis paniculata by solvent ethanol. The active ingredient of andrographis extract is generally andrographolide(cas#:5508-58-7). There are other diterpene lactones such as neoandrographolide, dehydroxyandrographolide and 14-deoxyandrographolide etc.
The natural herb Chuanxinlian
The herb andrographis paniculata is a small anual herb grows to between 30-90cm in height. It has many different names respectively in different language, In China-it is Chuanxinlian, In India-mostly Kalmegh, In Uk-Creat, king of bitters,Fa Thalai Chon in Thai. Andrographis herb is quite abundant in India and Guangxi,Hainan,Guangdong of China which with higher temperature and moisture.The slender stem of andrographis herb is dark green, squared in cross-section with longitudinal furrows and wings along the angles. The lance-shaped andrographis leaves have hairless blades measuring up to 8 cm (3.1 in) long by 2.5 cm (0.98 in). The small flowers are borne in spreading racemes in purple. The fruit of andrographis paniculata herb is a capsule around 2 cm (0.79 in) long and a few millimeters wide which contains many yellow-brown seeds. The sun dryed anrographis paninuclata herb is cutted before the extraction step starting.
How to apply the andrographis extract?
The application of herb andrographis paniculata has long history both in India Ayuda and Chinese TCM. And the new technology of extraction gives us convenient way to get the key ingredient of the herb by extraction. Andrographis extract is now widely applied in pharmaceutical, dietary supplement and cosmetics industrials.1) As pharmaceutical ingredient, Andrographolide is applied alleviating the symptoms of the common cold and fighting for the liver problems by capsules,granules and tablets in China. Andrographolide is also the intermediate for API Potassium Dehydroandrograpolide Succinate(C28H35KO10,cas#: 2216-51-5) and Potassium Sodium Dehydroandroan drographolide Suc cinate (C28H34KNaO10,cas#:73590-58-6) .In India,andrographis extract is applied for gastric disorders, liver support and diarrhea fighting.2)In dietary supplements, this bitter-tasting andrographolide acts important role for immune strength and liver support, and there’s some application in joint-health and memory improving.3)In beauty industry, andrographolide is for soothing, skin lightening, prevention of dark circle and spot prevention. 4) For our lovely pets, they are lucky to have natural ingredient andrographis extract to fighting diarrhea. Pet-lovers also apply this extract in to pet shampoo and soap to keep pets from flea things.5) It might be a good idea to use andrographis extract’s king of bitter as make non-bite pills.
How the natural herb becomes the extract powder?
MAOYUAN experienced in extraction of andrographis paniculata herb 10+ yuears and manufactures andrographis extract by standard extract .The yearly output of andrographis extract is more than 30,000kgs by MAOYUAN’s 10 extracting tanks.From MAOYUAN’s ISO9001&14001 factory, the andrographis extract meets both China and USA Pharmacopea. Here is how MAOYUAN manufactures the andrographis extract:
Process Flowsheet of Andrographis extract
MAOYUAN R&D Teams successfully get special color andrographis extract from light yellowish brown to green powder for andrographolide50% and lower specification extracts, they are available on customer’s special requirements. And here following are the specifications generally in stock and ready for shipment:
S/N | Extract | Specification | Appearance |
1 | Andrographis extract | Total andrographolide30% | Yellowish brown powder |
2 | Andrographis extract | Andrographolide5% | Yellowish brown powder |
3 | Andrographis extract | Andrographolide10% | Yellowish brown powder |
4 | Andrographis extract | Andrographolide20% | Light brown to yellow powder |
5 | Andrographis extract | Andrographolide30% | Light brown to yellow powder |
6 | Andrographis extract | Andrographolide50% | Off-white powder |
7 | Andrographis extract | White crystal powder | |
8 | Andrographis extract | Andrographolide99% | White crystal |
As you see, the specification of andrographis extract is classified by the assay of the andrographolide. The test method of the assay is HPLC on dry basis. It is lucky that all the andrographolide on the market now is naturally originated from the natural herb.
MAOYUAN-The factory focus on extract powder
Pengzhou Maoyuan Biochemical Technology Co., Ltd., founded in 2000, is an ISO14001&9001 certified manufacturer focusing on herbal extracts and plant extracts valued for Nutritional,Pharmaceutical and cosmeceutical industries. MAOYUAN’s processing site locates in Pengzhou Industrial Development Zone,Chengdu, with two cutting-edge extraction production lines, purification, drying and testing lab. We follow strict GMP regulations and will provide you with samples, testing reports and related certificates and statements such as, Certificate of Analysis and Material Safety Data Sheet. Focusing on the andrographis extract, MAOYUAN also manufactures camptothecin, Rutin, Honeysuckle extract and Gingko biloba extracts to customers worldwide with fast shipping time. Visit us at www.pzmybio.com
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